| Tag | Content |
|---|
| CPLM ID | CPLM-007235 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | 26S proteasome regulatory subunit RPN3 |
Protein Synonyms/Alias | |
Gene Name | RPN3 |
Gene Synonyms/Alias | SUN2; YER021W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 58 | RYIWRSLKDLSSLRN | acetylation | [1] | | 94 | SFKKNLLKFITSNHK | acetylation | [1] | | 350 | LPYYHLTKAVKLGDL | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. |
Sequence Annotation | DOMAIN 343 447 PCI.
MOD_RES 2 2 N-acetylalanine.
MOD_RES 454 454 Phosphoserine. |
Keyword | 3D-structure; Acetylation; Complete proteome; Direct protein sequencing; Phosphoprotein; Proteasome; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 523 AA |
Protein Sequence | MASTAVMMDV DSSGVNDLHH SEKKYAEEDQ VQELLKVLNE ISKTTLTLDP RYIWRSLKDL 60
SSLRNQELLN AETLCFTVNV LYPDSSSFKK NLLKFITSNH KSSVPGSAEL RNSYPASFYS 120
VNTEKKTIEV TAEINCFMHL LVQLFLWDSK ELEQLVEFNR KVVIPNLLCY YNLRSLNLIN 180
AKLWFYIYLS HETLARSSEE INSDNQNIIL RSTMMKFLKI ASLKHDNETK AMLINLILRD 240
FLNNGEVDSA SDFISKLEYP HTDVSSSLEA RYFFYLSKIN AIQLDYSTAN EYIIAAIRKA 300
PHNSKSLGFL QQSNKLHCCI QLLMGDIPEL SFFHQSNMQK SLLPYYHLTK AVKLGDLKKF 360
TSTITKYKQL LLKDDTYQLC VRLRSNVIKT GIRIISLTYK KISLRDICLK LNLDSEQTVE 420
YMVSRAIRDG VIEAKINHED GFIETTELLN IYDSEDPQQV FDERIKFANQ LHDEYLVSMR 480
YPEDKKTQQN EKSENGENDD DTLDGDLMDD MSDISDLDDL GFL 523 |
Gene Ontology | GO:0008541; C:proteasome regulatory particle, lid subcomplex; IDA:SGD. GO:0030234; F:enzyme regulator activity; IEA:InterPro. GO:0050790; P:regulation of catalytic activity; IEA:GOC. GO:0042176; P:regulation of protein catabolic process; IEA:InterPro. GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |