CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006394
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Syndecan-4 
Protein Synonyms/Alias
 SYND4; Ryudocan core protein 
Gene Name
 Sdc4 
Gene Synonyms/Alias
 Synd4 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
194GKKPIYKKAPTNEFYubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
 Cell surface proteoglycan that bears heparan sulfate. 
Sequence Annotation
 CARBOHYD 44 44 O-linked (Xyl...) (heparan sulfate)
 CARBOHYD 65 65 O-linked (Xyl...) (heparan sulfate)
 CARBOHYD 67 67 O-linked (Xyl...) (heparan sulfate)  
Keyword
 Complete proteome; Direct protein sequencing; Glycoprotein; Heparan sulfate; Membrane; Proteoglycan; Reference proteome; Secreted; Signal; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 202 AA 
Protein Sequence
MAPVCLFAPL LLLLLGGFPV APGESIRETE VIDPQDLLEG RYFSGALPDD EDAGGLEQDS 60
DFELSGSGDL DDTEEPRTFP EVISPLVPLD NHIPENAQPG IRVPSEPKEL EENEVIPKRV 120
PSDVGDDDVS NKVSMSSTSQ GSNIFERTEV LAALIVGGVV GILFAVFLIL LLVYRMKKKD 180
EGSYDLGKKP IYKKAPTNEF YA 202 
Gene Ontology
 GO:0009986; C:cell surface; IDA:RGD.
 GO:0043034; C:costamere; IDA:RGD.
 GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
 GO:0005925; C:focal adhesion; IDA:RGD.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0045121; C:membrane raft; IDA:RGD.
 GO:0001968; F:fibronectin binding; IDA:RGD.
 GO:0005080; F:protein kinase C binding; IDA:RGD.
 GO:0070053; F:thrombospondin receptor activity; IEA:Compara.
 GO:0007155; P:cell adhesion; NAS:RGD.
 GO:0007267; P:cell-cell signaling; NAS:RGD.
 GO:0051894; P:positive regulation of focal adhesion assembly; IMP:RGD.
 GO:0045860; P:positive regulation of protein kinase activity; IMP:RGD.
 GO:0051496; P:positive regulation of stress fiber assembly; IMP:RGD.
 GO:0001657; P:ureteric bud development; IEP:RGD. 
Interpro
 IPR003585; Neurexin-like.
 IPR001050; Syndecan. 
Pfam
 PF01034; Syndecan 
SMART
 SM00294; 4.1m 
PROSITE
 PS00964; SYNDECAN 
PRINTS