CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023332
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Apoptosis inhibitor 5 homolog 
Protein Synonyms/Alias
 API-5; Antiapoptosis clone 11 protein homolog; AAC-11 
Gene Name
 Aac11 
Gene Synonyms/Alias
 LD09852; CG6582 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
498FYSPPSGKYSNKVNQacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
 Antiapoptotic factor. Also known to efficiently suppress E2F1-induced apoptosis. 
Sequence Annotation
  
Keyword
 Apoptosis; Complete proteome; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 536 AA 
Protein Sequence
MDNIERLYKC YEILSEAGDK ISEHVDEYKE ILKAVKGTSK EKRLASQFIG NFFKHFPDLA 60
DTAIDAQFDL CEDDDTQIRR QAIKDLPKLC QGNADATIRV GDTLAQLLIL DDPTELQQVN 120
NSLLAIIKLD TKSSIAGLFQ QISTGDETTR ERCLKFIATK LLTMGPTVIT KEIEDYIVEE 180
IKKALQDVTA DEFHLCMTIL GATKLGSTIT GHAELVKLAT EQAELNNTDA DIIAVDDEVV 240
ERFIQCASAA APYFSKTIKS TAFVAHVCDK LLPIKTWNMI ATAVSQDQIQ LRLLKVFAEM 300
ITNTDKLDNA SERINAVYNV LLEYMPLPKL SDEDLGDTPP SFQFSHAECL LYALHTLGKN 360
HPNSLSFVED AEKLKDFRAR LQYLARGTQG YIKKLEESLK GKTGEELKTE ENQLKQTALK 420
TTSNINILIR DLFHSPPIFK HDIVLSWIVP KNNKLGKRHA PITFGEKAAA NGKDKDQEPE 480
KKSRPSNDQK FYSPPSGKYS NKVNQSYGNN NRTRQRGGGG GGGSGGGYRN RRFNKY 536 
Gene Ontology
 GO:0005634; C:nucleus; ISS:UniProtKB.
 GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
 GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
 GO:0022008; P:neurogenesis; IMP:FlyBase. 
Interpro
 IPR008383; API5.
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold. 
Pfam
 PF05918; API5 
SMART
  
PROSITE
  
PRINTS