CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004496
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Thiosulfate-binding protein 
Protein Synonyms/Alias
  
Gene Name
 cysP 
Gene Synonyms/Alias
 b2425; JW2418 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
101QILHDKGKLIPADWQacetylation[1]
146DLVRSDVKLIFPNPKacetylation[1]
253FPVAWVDKNVQANGTacetylation[1]
295NNPEVMDKLKDKFPQacetylation[1]
299VMDKLKDKFPQTELFacetylation[1]
320GSWPEVMKTHFTSGGacetylation[1]
331TSGGELDKLLAAGRNacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. This protein specifically binds thiosulfate and is involved in its transmembrane transport. 
Sequence Annotation
  
Keyword
 Complete proteome; Direct protein sequencing; Periplasm; Reference proteome; Signal; Sulfate transport; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 338 AA 
Protein Sequence
MAVNLLKKNS LALVASLLLA GHVQATELLN SSYDVSRELF AALNPPFEQQ WAKDNGGDKL 60
TIKQSHAGSS KQALAILQGL KADVVTYNQV TDVQILHDKG KLIPADWQSR LPNNSSPFYS 120
TMGFLVRKGN PKNIHDWNDL VRSDVKLIFP NPKTSGNARY TYLAAWGAAD KADGGDKGKT 180
EQFMTQFLKN VEVFDTGGRG ATTTFAERGL GDVLISFESE VNNIRKQYEA QGFEVVIPKT 240
NILAEFPVAW VDKNVQANGT EKAAKAYLNW LYSPQAQTII TDYYYRVNNP EVMDKLKDKF 300
PQTELFRVED KFGSWPEVMK THFTSGGELD KLLAAGRN 338 
Gene Ontology
 GO:0030288; C:outer membrane-bounded periplasmic space; IDA:EcoCyc.
 GO:0043168; F:anion binding; IMP:EcoCyc.
 GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro.
 GO:0015419; F:sulfate transmembrane-transporting ATPase activity; IEA:InterPro.
 GO:0008272; P:sulfate transport; IEA:UniProtKB-KW.
 GO:0006790; P:sulfur compound metabolic process; IDA:EcoCyc. 
Interpro
 IPR006059; Solute-bd_1_bac.
 IPR000957; Sulphate/thiosulphate-bd_CS.
 IPR005669; Thiosulph/SO4-bd. 
Pfam
 PF01547; SBP_bac_1 
SMART
  
PROSITE
 PS00401; PROK_SULFATE_BIND_1
 PS00757; PROK_SULFATE_BIND_2 
PRINTS