UniProt Accession

 RDM1_HUMAN; Q8NG50; A0JP55; A8MV46; A8MY68; A8MZ92; A8RCS5; A8RCT0; A8RCT5; A8RCT8; A8RCU3; A8RCU8; A8RCW0; A8RCW5 

Genbank Protein ID

 AB080728; EF488473; EF488474; EF488475; EF488476; EF488477; EF488478; EF488479; EF488480; EF488481; EF488482; AC004675; AC015849; BC038301; BC127190; BM559857 

Genbank Nucleotide ID

 BAC02562.1; ABS86950.1; ABS86951.1; ABS86952.1; ABS86953.1; ABS86954.1; ABS86955.1; ABS86956.1; ABS86957.1; ABS86958.1; ABS86959.1; AAI27191.1 

Protein Name

 RAD52 motif-containing protein 1 

Protein Synonyms/Alias

 RAD52 homolog B 

Gene Name

 RDM1 

Gene Synonyms/Alias

 RAD52B 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
100	VRLGTRHKAVQHQAL	ubiquitination	[1]
113	ALALNSSKCQELANY	ubiquitination	[1]
133	GCSKRIIKLQELSDL	ubiquitination	[1, 2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 May confer resistance to the antitumor agent cisplatin. Binds to DNA and RNA. 

Sequence Annotation

 DOMAIN 15 98 RRM.
 REGION 1 92 Necessary for nuclear localization and
 REGION 90 133 Necessary for nuclear and nucleolar  

Keyword

 Alternative promoter usage; Alternative splicing; Complete proteome; Cytoplasm; DNA-binding; Nucleus; Polymorphism; Reference proteome; RNA-binding. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 284 AA 

Protein Sequence

Gene Ontology

 GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005730; C:nucleolus; IDA:HPA.
 GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
 GO:0006310; P:DNA recombination; IEA:InterPro.
 GO:0006281; P:DNA repair; IEA:InterPro. 

Interpro

 IPR012677; Nucleotide-bd_a/b_plait.
 IPR007232; Rad52_Rad22.
 IPR000504; RRM_dom. 

Pfam

 PF04098; Rad52_Rad22
 PF00076; RRM_1 

SMART

  

PROSITE

 PS50102; RRM 

PRINTS