CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028655
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Diacylglycerol kinase zeta 
Protein Synonyms/Alias
  
Gene Name
 Dgkz 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
321LLVFVNPKSGGNQGAubiquitination[1]
388TLDQLRLKPPPPVAIubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 946 AA 
Protein Sequence
MAEGPGGGGP SGDRAASGRA AAEEVVRRRC RRPEEAEVFQ PWPEGSRNVA AGPLVEERFS 60
QMHLRKQVSY RKAITKSGLQ HLAPPPPTPG APCGESEEQI QSTVDWSESA VYGEHIWFET 120
NVSGDFCYVG EQHCVAKMLP KSAPRKKCAA CKIVVHTQCI KQLEKINFRC KPSFRESGSR 180
NVREPTFVRH HWVHRRRQDG KCRHCGKGFQ QKFTFHSKEI VAISCSWCKQ AYHSKVSCFM 240
MQQIEEPCSL GVHAAVVIPP TWILRARRPQ NTLKASKKKK RASFKRRSSK KGPEEGRWRP 300
FIIRPTPSPL MKPLLVFVNP KSGGNQGAKI IQSFLWYLNP RQVFDLSQGG PREALEMYRK 360
VHNLRILACG GDGTVGWILS TLDQLRLKPP PPVAILPLGT GNDLARTLNW GGGYTDEPVS 420
KILSHVEEGN VVQLDRWDLR AEPNPEAGPE ERDDGATDRL PLDVFNNYFS LGFDAHVTLE 480
FHESREANPE KFNSRFRNKM FYAGTAFSDF LMGSSKDLAK HIRVVCDGMD LTPKIQDLKP 540
QCIVFLNIPR YCAGTMPWGH PGEHHDFEPQ RHDDGYLEVI GFTMTSLAAL QVGGHGERLT 600
QCREVLLTTA KAIPVQVDGE PCKLSASRIR IALRNQATMV QKAKRRSTAP LHSDQQPVPE 660
QLRIQVSRVS MHDYEALHYD KEQLKEASVP LGTVVVPGDS DLELCRAHIE RLQREPDGAG 720
AKSPMCHQLS SKWCFLDATT ASRFYRIDRA QEHLNYVTEI AQDEIYILDP ELLGASARPD 780
LPTPTSPLPA SPCSPTPGSM QGDTALPQGE ELIEAAKRND CCKLQELHRA GGDLMHRDQK 840
SRTLLHHAVS TGSKEVVRYL LDHAPPEILD AVEENGETCL HQAAALGQRT ICHYIVEAGA 900
SLMKTDLQGD TPRQRAEKAQ DTELAAYLEN RQHYQMIQRE DQETAV 946 
Gene Ontology
 GO:0004143; F:diacylglycerol kinase activity; IEA:InterPro.
 GO:0004857; F:enzyme inhibitor activity; IDA:MGI.
 GO:0035556; P:intracellular signal transduction; IEA:InterPro.
 GO:0046580; P:negative regulation of Ras protein signal transduction; IMP:MGI.
 GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:InterPro. 
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom.
 IPR000756; Diacylglycerol_kin_accessory.
 IPR001206; Diacylglycerol_kinase_cat_dom.
 IPR002219; Prot_Kinase_C-like_PE/DAG-bd. 
Pfam
 PF12796; Ank_2
 PF00130; C1_1
 PF00609; DAGK_acc
 PF00781; DAGK_cat 
SMART
 SM00248; ANK
 SM00109; C1
 SM00045; DAGKa
 SM00046; DAGKc 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT
 PS50146; DAGK 
PRINTS