CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007238
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Factor interacting with REF2 
Protein Synonyms/Alias
 PAP1-interacting protein; Polymerase-interacting protein 1 
Gene Name
 FIR1 
Gene Synonyms/Alias
 PIP1; YER032W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
711EHNFIEEKRSIKNLGubiquitination[1]
715IEEKRSIKNLGHGPPubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Involved in 3' mRNA processing. Positively regulates poly(A) synthesis. 
Sequence Annotation
 MOD_RES 81 81 Phosphoserine.
 MOD_RES 172 172 Phosphoserine.
 MOD_RES 225 225 Phosphoserine.  
Keyword
 Complete proteome; mRNA processing; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 876 AA 
Protein Sequence
MSLPVTPVKS KVCSTLSIQH EMDHDQCRDV LCPRENLLAI NRTNNIESVA IPRQRSSKNK 60
KPHEHTQSQV RFSIPDPNEI SQDSPLKIVF PKSGNETERR MSTSSLLMNS HGHLVDMHSK 120
ILVDVPKEVW KFHHNRRKKC ESRHRKTRSD VRSNTSSSGK EPNHSRSKSL QSIIVDTMNT 180
YRATEVETSI NENTSNISQV SPLNLSFDRP PPLTPEKNLY LTPESPLNRY HLPVPLEISL 240
PPYLSPQNKD KKRSSLVYDG DGYSQFQEGN TSSSTESSLE QPSSSYSDED DSIPYAHHDV 300
SFELNNADAD KLLGIDENAN VNLKIQRRNL KNPQHIKSKT DRECEEKNTE KNVSLKILST 360
PNKLIDIPDL EHMKSPPSTG LNGTLKFFQQ FEPSEEPTSP TRQVNPESLD KLDMSFKFPS 420
STTNNNVDKV HENRNSGDTN NEDFLKVDTS PVNQSFESRR QMLIDLQKSP TNNNPRIHKH 480
RRSRSVHNID DISLNFEATS TPPAPTSAPS IPVEHSNPCT SIEIPKRSPL RFTSSPKTSD 540
IPPEAQSPKN GSFLQEISVP SIQIIPDESI SHTREPSPSL IECPEDENEA FSTEVADHSI 600
AIISETKSVP SIEPFKPLSS FNSFGQEIQN KEPTPLNQTP TDLIGKQRNC VNPHSIPFSV 660
LSSNSQSSQS GSSKSSYNSE FSSNTAITDT TSQPSVTINR STLEHNFIEE KRSIKNLGHG 720
PPSQKNNYSF PRNKNTPSNR HDLDFNTIYE KRDGKMVEVI LLDEDEDVGL KNNDISRTRV 780
CHAQKAKNEQ QKKRLSHCNE ILGMCDKTAD DAKRIIYQLV NEKHKFSEKG QQTKPKKSRV 840
LPPLPFPLYD EKGNSLIPNK YQSSIHNDIP SHRKLK 876 
Gene Ontology
 GO:0005935; C:cellular bud neck; IDA:SGD.
 GO:0006378; P:mRNA polyadenylation; IGI:SGD. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS