UniProt Accession

 J3KSP6_HUMAN; J3KSP6 

Genbank Protein ID

 AC012184; AC106804; CH471241 

Genbank Nucleotide ID

 EAW51817.1 

Protein Name

 Fucokinase, isoform CRA_d 

Protein Synonyms/Alias

 L-fucose kinase 

Gene Name

 FUK 

Gene Synonyms/Alias

 hCG_1774069 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
150	ALAQERDKWLSRPAL	ubiquitination	[1]
265	RQDEMTVKIVCRCLA	ubiquitination	[1]
398	SRAQLPLKVEVEEVT	ubiquitination	[2, 3]
425	LLLVYTGKTRLARNL	ubiquitination	[1, 3]
485	TSYWEQKKLMAPGCE	ubiquitination	[1]
531	LTKEPQQKEALEAVL	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

  

Sequence Annotation

  

Keyword

 ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 575 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
 GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro. 

Interpro

 IPR013750; GHMP_kinase_C_dom.
 IPR006204; GHMP_kinase_N_dom.
 IPR006206; Mevalonate/galactokinase.
 IPR020568; Ribosomal_S5_D2-typ_fold.
 IPR014721; Ribosomal_S5_D2-typ_fold_subgr. 

Pfam

 PF08544; GHMP_kinases_C
 PF00288; GHMP_kinases_N 

SMART

  

PROSITE

  

PRINTS

 PR00959; MEVGALKINASE.