CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028539
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Dystrophin 
Protein Synonyms/Alias
  
Gene Name
 Dmd 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
6**MREHLKGHETQTTubiquitination[1]
152DKYRYLFKQVASSTGubiquitination[1]
240VAAAETAKHQAKCNIubiquitination[1]
482AELIAEAKLLRQHKGubiquitination[1]
503QILEDHNKQLESQLHubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 604 AA 
Protein Sequence
MREHLKGHET QTTCWDHPKM TELYQSLADL NNVRFSAYRT AMKLRRLQKA LCLDLLSLSA 60
ACDALDQHNL KQNDQPMDIL QIINCLTTIY DRLEQEHNNL VNVPLCVDMC LNWLLNVYDT 120
GRTGRIRVLS FKTGIISLCK AHLEDKYRYL FKQVASSTGF CDQRRLGLLL HDSIQIPRQL 180
GEVASFGGSN IEPSVRSCFQ FANNKPEIEA ALFLDWMRLE PQSMVWLPVL HRVAAAETAK 240
HQAKCNICKE CPIIGFRYRS LKHFNYDICQ SCFFSGRVAK GHKMHYPMVE YCTPTTSGED 300
VRDFAKVLKN KFRTKRYFAK HPRMGYLPVQ TVLEGDNMET PASSPQLSHD DTHSRIEHYA 360
SRLAEMENSN GSYLNDSISP NESIDDEHLL IQHYCQSLNQ DSPLSQPRSP AQILISLESE 420
ERGELERILA DLEEENRNLQ AEYDRLKQQH EHKGLSPLPS PPEMMPTSPQ SPRDAELIAE 480
AKLLRQHKGR LEARMQILED HNKQLESQLH RLRQLLEQPQ AEAKVNGTTV SSPSTSLQRS 540
DSSQPMLLRV VGSQTSESMG EEDLLSPPQD TSTGLEEVME QLNNSFPSSR GRNAPGKPMR 600
EDTM 604 
Gene Ontology
 GO:0030055; C:cell-substrate junction; IDA:MGI.
 GO:0016010; C:dystrophin-associated glycoprotein complex; IDA:MGI.
 GO:0045121; C:membrane raft; IDA:MGI.
 GO:0044306; C:neuron projection terminus; IDA:MGI.
 GO:0042383; C:sarcolemma; IDA:MGI.
 GO:0045202; C:synapse; IDA:MGI.
 GO:0030018; C:Z disc; IDA:MGI.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0008065; P:establishment of blood-nerve barrier; IMP:MGI.
 GO:0060857; P:establishment of glial blood-brain barrier; IMP:MGI.
 GO:0046716; P:muscle cell homeostasis; IMP:MGI.
 GO:0048747; P:muscle fiber development; IGI:MGI.
 GO:0014904; P:myotube cell development; IMP:MGI.
 GO:0045213; P:neurotransmitter receptor metabolic process; IMP:MGI.
 GO:0051647; P:nucleus localization; IMP:MGI.
 GO:0021629; P:olfactory nerve structural organization; IMP:MGI.
 GO:0006355; P:regulation of transcription, DNA-dependent; IMP:MGI. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR015153; EF-hand_dom_typ1.
 IPR015154; EF-hand_dom_typ2.
 IPR000433; Znf_ZZ. 
Pfam
 PF09068; efhand_1
 PF09069; efhand_2
 PF00569; ZZ 
SMART
 SM00291; ZnF_ZZ 
PROSITE
 PS01357; ZF_ZZ_1
 PS50135; ZF_ZZ_2 
PRINTS