CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011294
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein PAL1 
Protein Synonyms/Alias
 Pears and lemons protein 1 
Gene Name
 PAL1 
Gene Synonyms/Alias
 YDR348C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
32DSSINQYKNDSQFQEubiquitination[1]
42SQFQEWAKNQSRTNSubiquitination[1]
135NKNHPTAKEEKEQLRubiquitination[2]
138HPTAKEEKEQLRQRYubiquitination[2]
184RRAYPKEKVSRPSSHubiquitination[1, 2]
269PHRNKNNKAAPVLAFubiquitination[1]
291TIGGASTKKSALDEVubiquitination[2]
292IGGASTKKSALDEVFubiquitination[2]
328GDTQDAIKANVGNVQubiquitination[1, 2]
340NVQQMDAKNKTELVHubiquitination[1, 2]
342QQMDAKNKTELVHGPubiquitination[1]
375AAIRNDIKAHSYHNRubiquitination[1]
435NEGVRRSKTVNSPNRubiquitination[1]
445NSPNRTHKSNYTTDFubiquitination[1, 2]
484KKKSTGSKLLSRVKSubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047] 
Functional Description
 Involved in the early step of endocytosis. 
Sequence Annotation
 MOD_RES 14 14 Phosphoserine.
 MOD_RES 45 45 Phosphoserine.
 MOD_RES 47 47 Phosphothreonine.
 MOD_RES 49 49 Phosphoserine.
 MOD_RES 64 64 Phosphoserine.
 MOD_RES 114 114 Phosphoserine.
 MOD_RES 121 121 Phosphoserine.
 MOD_RES 153 153 Phosphothreonine.
 MOD_RES 304 304 Phosphothreonine.
 MOD_RES 307 307 Phosphoserine.  
Keyword
 Cell membrane; Complete proteome; Endocytosis; Membrane; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 499 AA 
Protein Sequence
MENRNSSTSS RPFSVNNPFR NATVDSSINQ YKNDSQFQEW AKNQSRTNSF DMPQLNTRTS 60
SQLSFPNIPE DEPQRNADQQ GAFYSGLESF SSGSLSPPSR PLSSKNPFLD DVSSATDFRR 120
SPPPVSRNKN HPTAKEEKEQ LRQRYLEESD VSTVGNTREN TDLPPSYEEI TSTNGSRRAY 180
PKEKVSRPSS HREHSNSGTY ISRRSSSHHH REASSSSTPS KKGKRKSKVI VPKNVDTIDK 240
LDVTGLFGGS FHHDGPFDAV TPHRNKNNKA APVLAFPVDG PNSTIGGAST KKSALDEVFG 300
RDDTDDSDIY QYSSQTLRRG GDTQDAIKAN VGNVQQMDAK NKTELVHGPV TAGLGSSTFL 360
DGAPASSAAI RNDIKAHSYH NRNGGLQRNK SLSQRLGLGG SGDSNAPMTG VRRNLSLSRD 420
NYDVGHSNEG VRRSKTVNSP NRTHKSNYTT DFDGQDDHNE DEEDVYLGVR YNEPNMKKKS 480
TGSKLLSRVK SLKVGRKSQ 499 
Gene Ontology
 GO:0005938; C:cell cortex; IDA:SGD.
 GO:0005935; C:cellular bud neck; IDA:SGD.
 GO:0005934; C:cellular bud tip; IDA:SGD.
 GO:0043332; C:mating projection tip; IDA:SGD.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0006897; P:endocytosis; IEA:UniProtKB-KW. 
Interpro
 IPR013226; Pal1. 
Pfam
 PF08316; Pal1 
SMART
  
PROSITE
  
PRINTS