CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026521
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MKIAA0002 protein 
Protein Synonyms/Alias
  
Gene Name
 Cct8 
Gene Synonyms/Alias
 mKIAA0002 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
14AMALHVPKAPGFAQMubiquitination[1]
23PGFAQMLKDGAKHFSubiquitination[1]
69MVINRLEKLFVTNDAubiquitination[1]
242EGDVTSVKDAKIAVYubiquitination[1]
261DGMITETKGTVLIKTubiquitination[1]
267TKGTVLIKTAEELMNubiquitination[1]
277EELMNFSKGEENLMDubiquitination[1]
303NVIVTGGKVADIALHubiquitination[1]
374VVVFKHEKEDGAISTubiquitination[1]
407DDGVNTFKVLTRDKRubiquitination[1]
428ATEIELAKQITSYGEubiquitination[1]
447LEQYAIKKFAEAFEAubiquitination[1]
466LAENSGVKANEVISKubiquitination[1]
535VDQIIMAKPAGGPKPubiquitination[1]
541AKPAGGPKPPSGKKDubiquitination[1]
546GPKPPSGKKDWDDDQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Chaperone; Cytoplasm; Nucleotide-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 555 AA 
Protein Sequence
AVDCGRAMAL HVPKAPGFAQ MLKDGAKHFS GLEEAVYRNI QACKELAQTT RTAYGPNGMN 60
KMVINRLEKL FVTNDAATIL RELEVQHPAA KMIVMASHMQ EQEVGDGTNF VLVFAGALLE 120
LAEELLRIGL SVSEVISGYE IACKKAHEIL PELVCCSAKN LRDVDEVSSL LRTSIMSKQY 180
GSETFLAKLI AQACVSIFPD SGNFNVDNIR VCKILGSGIY SSSVLHGMVF KKETEGDVTS 240
VKDAKIAVYS CPFDGMITET KGTVLIKTAE ELMNFSKGEE NLMDAQVKAI AGTGANVIVT 300
GGKVADIALH YANKYNIMLV RLNSKWDLRR LCKTVGATAL PKLTPPVQEE MGHCDSVYLS 360
EVGDTQVVVF KHEKEDGAIS TIVLRGSTDN LMDDIERAVD DGVNTFKVLT RDKRLVPGGG 420
ATEIELAKQI TSYGETCPGL EQYAIKKFAE AFEAIPRALA ENSGVKANEV ISKLYSVHQE 480
GNKNVGLDIE AEVPAVKDML EASILDTYLG KYWAIKLATN AAVTVLRVDQ IIMAKPAGGP 540
KPPSGKKDWD DDQND 555 
Gene Ontology
 GO:0016235; C:aggresome; IEA:Compara.
 GO:0044297; C:cell body; IDA:MGI.
 GO:0005813; C:centrosome; IEA:Compara.
 GO:0005832; C:chaperonin-containing T-complex; IDA:MGI.
 GO:0045111; C:intermediate filament cytoskeleton; IEA:Compara.
 GO:0005874; C:microtubule; IEA:Compara.
 GO:0002199; C:zona pellucida receptor complex; IDA:MGI.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0007339; P:binding of sperm to zona pellucida; IDA:MGI.
 GO:0006457; P:protein folding; IEA:InterPro. 
Interpro
 IPR012721; Chap_CCT_theta.
 IPR017998; Chaperone_TCP-1.
 IPR002194; Chaperonin_TCP-1_CS.
 IPR002423; Cpn60/TCP-1.
 IPR027409; GroEL-like_apical_dom.
 IPR027413; GROEL-like_equatorial.
 IPR027410; TCP-1-like_intermed. 
Pfam
 PF00118; Cpn60_TCP1 
SMART
  
PROSITE
 PS00750; TCP1_1
 PS00751; TCP1_2
 PS00995; TCP1_3 
PRINTS
 PR00304; TCOMPLEXTCP1.