CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038561
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Ribosome-releasing factor 2, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 Gfm2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
378AFKVLHDKQRGPLVFacetylation[1]
Reference
 [1] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; GTP-binding; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 741 AA 
Protein Sequence
MFTKWRIFAV NHQRTFSVHL NTMCYCKIKA NLKRLKTQLP LTRNYSSAPG IAGSDVKSLH 60
SVINPPVAKI RNIGIMAHID AGKTTTTERI LYYSGYTRSL GDVDDGDTVT DFMAQERERG 120
ITIQSAAVTL DWKGYRVNLI DTPGHVDFTL EVERCLRVLD GAVAVFDASA GVEAQTLTVW 180
RQADKHKIPR ICFLNKMDKT GASFNYAVES IREKLKAKPL ILQLPIGEAR TFQGVVDVVN 240
KEKLLWNSNS DDGKDFERMP LSEASDRELL KETIEARNSL IEQVADLDDE FADLVLGEFS 300
ENFDLVPAEK LQAAVHRVTL AQAAVPVLCG SALKNKGVQP LLDAVTTYLP SPEEREDRFL 360
QWYEGDLCAL AFKVLHDKQR GPLVFLRIYS GTLTPQLAVH NINRNCTERM SRLLLPFADQ 420
HVEIPSLTAG NIALTVGLKQ TATGDTIVSS KSSALAAARR AGRGEREHGK KREAESLLLA 480
GVEVPEPVFF CTIEPPSVAK QPDLDHALER LQREDPSLKV KLDPDSGQTV LCGMGELHIE 540
IIHDRIKREY GLETYLGPLQ VAYRETILNS VRATDTLDRV LGDKRHLVSA ELEVRPAEEP 600
CAVAKIEYAD CVGEDLLQAS REAIESAVHS ACLQGPLLGS PVQDVAMTLH SLMIHPGTST 660
TMVTACISRC MQKALKKADK QVLEPLMSLE VTVSREYLSP VLADLAQRRG NIQEIQTRQD 720
NRVVLGFVPL AEIMSLQLAD G 741 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0006184; P:GTP catabolic process; IEA:GOC. 
Interpro
 IPR000795; EF_GTP-bd_dom.
 IPR009022; EFG_III-V.
 IPR000640; EFG_V.
 IPR027417; P-loop_NTPase.
 IPR020568; Ribosomal_S5_D2-typ_fold.
 IPR014721; Ribosomal_S5_D2-typ_fold_subgr.
 IPR005225; Small_GTP-bd_dom.
 IPR005517; Transl_elong_EFG/EF2_IV.
 IPR004161; Transl_elong_EFTu/EF1A_2.
 IPR009000; Transl_elong_init/rib_B-barrel. 
Pfam
 PF00679; EFG_C
 PF03764; EFG_IV
 PF00009; GTP_EFTU
 PF03144; GTP_EFTU_D2 
SMART
 SM00838; EFG_C
 SM00889; EFG_IV 
PROSITE
 PS00301; EFACTOR_GTP 
PRINTS
 PR00315; ELONGATNFCT.