UniProt Accession

 TBL2_MOUSE; Q9R099; Q8CFY0 

Genbank Protein ID

 AF097523; AK132366; AK165686; BC039273; BC048185 

Genbank Nucleotide ID

 AAF06825.1; BAE21128.1; BAE38338.1; AAH39273.1; AAH48185.1 

Protein Name

 Transducin beta-like protein 2 

Protein Synonyms/Alias

  

Gene Name

 Tbl2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
116	TVRIWSTKDFLQREH	acetylation	[1]
116	TVRIWSTKDFLQREH	ubiquitination	[2]
310	DTDVEYKKQQDPYLL	ubiquitination	[2]
412	EEMQSLLKRASSEST	ubiquitination	[2]
435	TQAQEALKSLGALKK	ubiquitination	[2]

Reference

 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

 REPEAT 84 123 WD 1.
 REPEAT 130 170 WD 2.
 REPEAT 182 222 WD 3.
 REPEAT 224 263 WD 4.
 REPEAT 273 312 WD 5.
 REPEAT 323 362 WD 6.
 REPEAT 366 404 WD 7.
 MOD_RES 428 428 Phosphothreonine (By similarity).  

Keyword

 Complete proteome; Phosphoprotein; Reference proteome; Repeat; WD repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 442 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR020472; G-protein_beta_WD-40_rep.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 

Pfam

 PF00400; WD40 

SMART

 SM00320; WD40 

PROSITE

 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 

PRINTS

 PR00320; GPROTEINBRPT.