Tag | Content |
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CPLM ID | CPLM-017504 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 614 |
Protein Synonyms/Alias | |
Gene Name | ZNF614 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
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99 | SPNQRLLKSVQQCNG | ubiquitination | [1] |
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Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 8 79 KRAB. ZN_FING 205 227 C2H2-type 1; atypical. ZN_FING 257 281 C2H2-type 2; degenerate. ZN_FING 287 309 C2H2-type 3. ZN_FING 315 337 C2H2-type 4. ZN_FING 343 365 C2H2-type 5. ZN_FING 371 393 C2H2-type 6. ZN_FING 399 421 C2H2-type 7. ZN_FING 427 449 C2H2-type 8. ZN_FING 455 477 C2H2-type 9. ZN_FING 483 505 C2H2-type 10. ZN_FING 511 533 C2H2-type 11. ZN_FING 539 561 C2H2-type 12. |
Keyword | Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 585 AA |
Protein Sequence | MIKTQESLTL EDVAVEFSWE EWQLLDTAQK NLYRDVMVEN YNHLVSLGYQ TSKPDVLSKL 60 AHGQEPWTTD AKIQNKNCPG IGKVDSHLQE HSPNQRLLKS VQQCNGQNTL RNIVHLSKTH 120 FPIVQNHDTF DLYRKNLKSS LSLINQKRRH GINNPVEFIG GEKTLLHGKH ERTHTKTRFS 180 ENAKCIHTKF QVFKHQRTQK IEKPHACIEC EQTFLRKSQL IYHENICIQE NPGSGQCEKL 240 SRSVLFTKHL KTNTTDKICI PNEYRKGSTV KSSLITHQQT HTEEKSYMCS ECGKGFTMKR 300 YLIAHQRTHS GEKPYVCKEC GKGFTVKSNL IVHQRTHTGE KPYICSECGK GFTMKRYLVV 360 HQRTHTGEKP YMCSECGKGF TVKSNLIVHQ RSHTGEKSYI CSECGKGFTV KRTLVIHQRT 420 HTGEKSYICN ECGKGFTTKR TLIIHQRTHT GEKPYECNEC GKAFSQKICL IQHERCHTGK 480 TPFVCTECGK SYSHKYGLIT HQRIHTGEKP YECNECGKAF TTKSVLNVHQ RTHTGERPYG 540 CSDCEKAFSH LSNLVKHKKM HTREMGRISQ VENSCNGESQ LLPYK 585 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |