CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004524
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 37A 
Protein Synonyms/Alias
 Zinc finger protein KOX21 
Gene Name
 ZNF37A 
Gene Synonyms/Alias
 KOX21; ZNF37 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
339CGKSFSEKSTLTQHQubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 8 79 KRAB.
 ZN_FING 146 168 C2H2-type 1; degenerate.
 ZN_FING 243 265 C2H2-type 2; degenerate.
 ZN_FING 271 293 C2H2-type 3.
 ZN_FING 299 321 C2H2-type 4.
 ZN_FING 327 349 C2H2-type 5.
 ZN_FING 355 377 C2H2-type 6.
 ZN_FING 383 405 C2H2-type 7.
 ZN_FING 411 433 C2H2-type 8.
 ZN_FING 439 461 C2H2-type 9.
 ZN_FING 467 489 C2H2-type 10.
 ZN_FING 495 517 C2H2-type 11.
 ZN_FING 523 545 C2H2-type 12.  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 561 AA 
Protein Sequence
MITSQGSVSF RDVTVGFTQE EWQHLDPAQR TLYRDVMLEN YSHLVSVGYC IPKPEVILKL 60
EKGEEPWILE EKFPSQSHLE LINTSRNYSI MKFNEFNKGG KCFCDEKHEI IHSEEEPSEY 120
NKNGNSFWLN EDLIWHQKIK NWEQSFEYNE CGKAFPENSL FLVHKRGYTG QKTCKYTEHG 180
KTCDMSFFIT HQQTHPRENH YGNECGENIF EESILLEHQS VYPFSQKLNL TPIQRTHSIN 240
NIIEYNECGT FFSEKLVLHL QQRTHTGEKP YECHECGKTF TQKSAHTRHQ RTHTGGKPYE 300
CHECGKTFYK NSDLIKHQRI HTGERPYGCH ECGKSFSEKS TLTQHQRTHT GEKPYECHEC 360
GKTFSFKSVL TVHQKTHTGE KPYECYACGK AFLRKSDLIK HQRIHTGEKP YECNECGKSF 420
SEKSTLTKHL RTHTGEKPYE CIQCGKFFCY YSGFTEHLRR HTGEKPFGCN ECGKTFRQKS 480
ALIVHQRTHI RQKPYGCNQC GKSFCVKSKL IAHHRTHTGE KPYECNVCGK SFYVKSKLTV 540
HQRIHLGRNP INVVNEGNYS G 561 
Gene Ontology
 GO:0005634; C:nucleus; NAS:UniProtKB.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS