CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025808
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 COP9 constitutive photomorphogenic homolog subunit 2 variant 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
434ARYTALDKWTNQLNSubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 451 AA 
Protein Sequence
KMSDMEDDFM CDDEEDYDLE YSEDSNSEPN VDLENQYYNS KALKEDDPKA ALSSFQKVLE 60
LEGEKGEWGF KALKQMIKIN FKLTNFPEMM NRYKQLLTYI RSAVTRNYSE KSINSILDYI 120
STSKQNSDFL CQMDLLQEFY ETTLEALKDA KNDRLWFKTN TKLGKLYLER EEYGKLQKIL 180
RQLHQSCQTD DGEDDLKKGT QLLEIYALEI QMYTAQKNNK KLKALYEQSL HIKSAIPHPL 240
IMGVIRECGG KMHLREGEFE KAHTDFFEAF KNYDESGSPR RTTCLKYLVL ANMLMKSGIN 300
PFDSQEAKPY KNDPEILAMT NLVSAYQNND ITEFEKILKT NHSNIMDDPF IREHIEELLR 360
NIRTQVLIKL IKPYTRIHIP FISKELNIDV ADVESLLVQC ILDNTIHGRI DQVNQLLELD 420
HQKRGGARYT ALDKWTNQLN SLNQAVVSKL A 451 
Gene Ontology
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0003714; F:transcription corepressor activity; IEA:Compara.
 GO:0008283; P:cell proliferation; IEA:Compara.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0030182; P:neuron differentiation; IEA:Compara. 
Interpro
 IPR013143; PAM.
 IPR000717; PCI_dom.
 IPR011990; TPR-like_helical.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF01399; PCI 
SMART
 SM00753; PAM
 SM00088; PINT 
PROSITE
  
PRINTS