| Tag | Content |
|---|
| CPLM ID | CPLM-010206 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | HTH-type transcriptional repressor ComR |
Protein Synonyms/Alias | Copper outer membrane regulator |
Gene Name | comR |
Gene Synonyms/Alias | ycfQ; b1111; JW5159 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 27 | DRDAALDKAMKLFWQ | acetylation | [1] | | 81 | YIDRFAAKHEAQLFC | acetylation | [1] | | 193 | REGASLEKLMQIAGT | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Represses expression of BhsA/ComC by binding to its promoter region in the absence of copper. |
Sequence Annotation | DOMAIN 18 78 HTH tetR-type.
DNA_BIND 41 60 H-T-H motif (Potential). |
Keyword | Complete proteome; Copper; DNA-binding; Reference proteome; Repressor; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 210 AA |
Protein Sequence | MATDSTQCVK KSRGRPKVFD RDAALDKAMK LFWQHGYEAT SLADLVEATG AKAPTLYAEF 60
TNKEGLFRAV LDRYIDRFAA KHEAQLFCEE KSVESALADY FAAIANCFTS KDTPAGCFMI 120
NNCTTLSPDS GDIANTLKSR HAMQERTLQQ FLCQRQARGE IPPHCDVTHL AEFLNCIIQG 180
MSISAREGAS LEKLMQIAGT TLRLWPELVK 210 |
Gene Ontology | GO:0003677; F:DNA binding; IDA:EcoCyc. GO:0045892; P:negative regulation of transcription, DNA-dependent; IEP:EcoCyc. GO:0046688; P:response to copper ion; IDA:EcoCyc. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |