UniProt Accession

 F1LQ90_RAT; F1LQ90 

Genbank Protein ID

 AABR06095739; AABR06095740 

Genbank Nucleotide ID

  

Protein Name

 Transcription factor 4 

Protein Synonyms/Alias

  

Gene Name

 Tcf4 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
460	DDDKKDIKSITRSRS	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 589 AA 

Protein Sequence

Gene Ontology

 GO:0005667; C:transcription factor complex; IEA:Compara.
 GO:0070888; F:E-box binding; IEA:Compara.
 GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IEA:Compara.
 GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Compara.
 GO:0001011; F:sequence-specific DNA binding RNA polymerase recruiting transcription factor activity; IEA:Compara.
 GO:0001087; F:TFIIB-class binding transcription factor activity; IEA:Compara.
 GO:0003714; F:transcription corepressor activity; IEA:Compara.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0045666; P:positive regulation of neuron differentiation; IEA:Compara.
 GO:0065004; P:protein-DNA complex assembly; IEA:Compara.
 GO:0006367; P:transcription initiation from RNA polymerase II promoter; IEA:Compara. 

Interpro

 IPR011598; bHLH_dom. 

Pfam

 PF00010; HLH 

SMART

 SM00353; HLH 

PROSITE

 PS50888; BHLH 

PRINTS