UniProt Accession

 EBP2_HUMAN; Q99848; Q96A66 

Genbank Protein ID

 U86602; BC009175 

Genbank Nucleotide ID

 AAB46731.1; AAH09175.1 

Protein Name

 Probable rRNA-processing protein EBP2 

Protein Synonyms/Alias

 EBNA1-binding protein 2; Nucleolar protein p40 

Gene Name

 EBNA1BP2 

Gene Synonyms/Alias

 EBP2 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
33	AFSRGLLKPGLNVVL	ubiquitination	[1]
94	APQNKDQKAVDPEDD	ubiquitination	[2]
209	YQKGFSDKLDFLEGD	ubiquitination	[1]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 Required for the processing of the 27S pre-rRNA (By similarity). 

Sequence Annotation

 MOD_RES 1 1 N-acetylmethionine.
 MOD_RES 3 3 Phosphothreonine.
 MOD_RES 7 7 Phosphoserine.
 MOD_RES 9 9 Phosphoserine.
 MOD_RES 11 11 Phosphoserine.
 MOD_RES 13 13 Phosphoserine.
 MOD_RES 16 16 Phosphoserine.
 MOD_RES 270 270 Phosphoserine.  

Keyword

 Acetylation; Coiled coil; Complete proteome; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Ribosome biogenesis. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 306 AA 

Protein Sequence

Gene Ontology

 GO:0016020; C:membrane; TAS:ProtInc.
 GO:0005730; C:nucleolus; IDA:HPA.
 GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW. 

Interpro

 IPR008610; Ebp2. 

Pfam

 PF05890; Ebp2 

SMART

  

PROSITE

  

PRINTS