CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009365
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Neurocalcin-delta 
Protein Synonyms/Alias
  
Gene Name
 NCALD 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
50LSMEEFKKIYGNFFPubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
 May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions. 
Sequence Annotation
 DOMAIN 23 58 EF-hand 1.
 DOMAIN 60 95 EF-hand 2.
 DOMAIN 96 131 EF-hand 3.
 DOMAIN 144 179 EF-hand 4.
 LIPID 2 2 N-myristoyl glycine (By similarity).  
Keyword
 Calcium; Complete proteome; Lipoprotein; Metal-binding; Myristate; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 193 AA 
Protein Sequence
MGKQNSKLRP EVMQDLLEST DFTEHEIQEW YKGFLRDCPS GHLSMEEFKK IYGNFFPYGD 60
ASKFAEHVFR TFDANGDGTI DFREFIIALS VTSRGKLEQK LKWAFSMYDL DGNGYISKAE 120
MLEIVQAIYK MVSSVMKMPE DESTPEKRTE KIFRQMDTNR DGKLSLEEFI RGAKSDPSIV 180
RLLQCDPSSA GQF 193 
Gene Ontology
 GO:0030130; C:clathrin coat of trans-Golgi network vesicle; NAS:UniProtKB.
 GO:0005829; C:cytosol; NAS:UniProtKB.
 GO:0003779; F:actin binding; IDA:UniProtKB.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0030276; F:clathrin binding; IDA:UniProtKB.
 GO:0015631; F:tubulin binding; IDA:UniProtKB.
 GO:0007268; P:synaptic transmission; TAS:Reactome.
 GO:0016192; P:vesicle-mediated transport; NAS:UniProtKB. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom.
 IPR001125; Recoverin. 
Pfam
 PF13499; EF_hand_5
 PF00036; efhand 
SMART
 SM00054; EFh 
PROSITE
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 
PRINTS
 PR00450; RECOVERIN.