CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017853
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nucleolar protein 14 
Protein Synonyms/Alias
 Nucleolar complex protein 14 
Gene Name
 Nop14 
Gene Synonyms/Alias
 Nol14 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
775QFTPRLVKVLEFGRKacetylation[1]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441
Functional Description
 Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity). 
Sequence Annotation
 MOD_RES 96 96 Phosphoserine (By similarity).
 MOD_RES 146 146 Phosphoserine.
 MOD_RES 148 148 Phosphoserine.
 MOD_RES 346 346 Phosphoserine (By similarity).  
Keyword
 Complete proteome; Nucleus; Phosphoprotein; Reference proteome; Ribosome biogenesis; rRNA processing. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 860 AA 
Protein Sequence
MGKAKRTGAR RQVHKAPAGA SGGPAKTNPN PFEVKVNRQK FQILGRKTRH DVGLPGVSRA 60
RAIRKRTQTL LKEYKERNKS NVFADKRFGE YNSNISPEEK MMKRFALEQQ RYHEKKNIYN 120
LNEDEELTHY GQSLADIEKH NDIVDSDSDT EDRGALSAEL TASHFGGGVH KNSSQKEGED 180
GDKPKTRKEL IEELIAKSKQ EKRERQAQRE DALELTEKLD QDWKEIQILM SRKPKKSEDK 240
EKKEKPQPDE YDMMVRELGF EMKAQPSNRM KTEEELAKEE QERLKKLEAE RLRRMLGKDE 300
HENKKKPKHT SADDLNDGFI LDKDDRRLLS YKDGKMNIED VQEEQSKEAD GQENDQKEGE 360
DDSEEEDESH EDSEESEDPD SHSDLESNIE SEEENETPKK EQRQTPGGKL PKDDQKAQKA 420
VAAELPYVFA APESFEELKF LLSGRSMEEQ LLVVERIQKC NHPSLAVGNK AKLEKLFGFL 480
LQYIGDLATD STPDLKTIDK LVVHLYSLCQ MFPESASDSI RFVLRDAMHE MEEMIETKGR 540
AAFPGLDVLI YLKITGLLFP TSDFWHPVVT PALLCMSQML TKCPVMSLQD VIKGLFVCCL 600
FLEYVSLSRR FIPELFNFLL GILYIATPNT KSQGSTLVHP FRALGKNSEL LVVSDKADVT 660
TWQRGSLPLH WANRLSTLTA TEANHTRLSC VASCLSLMKH CVLMYQALPS FHAIFRPHQA 720
LLSKHLADCS LPQELQELAQ SILSAMEGQK QHCRPLVCEK SKPVPLKQFT PRLVKVLEFG 780
RKQGSSKEEQ ERKRLIHKHK REFKGAVREI RKDNQFLARM QLSEIMERDA ERKRKVKQLF 840
NSLATQEGEW KALKRKKFKK 860 
Gene Ontology
 GO:0005730; C:nucleolus; ISS:UniProtKB.
 GO:0032040; C:small-subunit processome; IEA:InterPro.
 GO:0030515; F:snoRNA binding; ISS:UniProtKB.
 GO:0042274; P:ribosomal small subunit biogenesis; ISS:UniProtKB.
 GO:0006364; P:rRNA processing; IEA:UniProtKB-KW. 
Interpro
 IPR007276; Nop14. 
Pfam
 PF04147; Nop14 
SMART
  
PROSITE
  
PRINTS