CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006425
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ribosome assembly protein SQT1 
Protein Synonyms/Alias
  
Gene Name
 SQT1 
Gene Synonyms/Alias
 YIR012W; YIB12W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
250KITQAEIKGLEAPWIubiquitination[1]
348SAWRVRHKFVLEDSVacetylation[2]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 
Functional Description
 May be involved in the late step of 60S ribosomal subunit assembly or modification in the cytoplasm. 
Sequence Annotation
 REPEAT 63 102 WD 1.
 REPEAT 107 146 WD 2.
 REPEAT 149 192 WD 3.
 REPEAT 199 243 WD 4.
 REPEAT 309 348 WD 5.
 REPEAT 350 387 WD 6.  
Keyword
 Complete proteome; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 431 AA 
Protein Sequence
MEPQEEFITT EEVEQEIVPT VEVEQDVPVD IEGENDDDDE MMNDDEEALE VDMSNNSLTY 60
FDKHTDSVFA IGHHPNLPLV CTGGGDNLAH LWTSHSQPPK FAGTLTGYGE SVISCSFTSE 120
GGFLVTADMS GKVLVHMGQK GGAQWKLASQ MQEVEEIVWL KTHPTIARTF AFGATDGSVW 180
CYQINEQDGS LEQLMSGFVH QQDCSMGEFI NTDKGENTLE LVTCSLDSTI VAWNCFTGQQ 240
LFKITQAEIK GLEAPWISLS LAPETLTKGN SGVVACGSNN GLLAVINCNN GGAILHLSTV 300
IELKPEQDEL DASIESISWS SKFSLMAIGL VCGEILLYDT SAWRVRHKFV LEDSVTKLMF 360
DNDDLFASCI NGKVYQFNAR TGQEKFVCVG HNMGVLDFIL LHPVANTGTE QKRKVITAGD 420
EGVSLVFEVP N 431 
Gene Ontology
 GO:0022626; C:cytosolic ribosome; IDA:SGD.
 GO:0000027; P:ribosomal large subunit assembly; IGI:SGD. 
Interpro
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS