CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036489
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Mroh1 
Protein Synonyms/Alias
  
Gene Name
 Mroh1 
Gene Synonyms/Alias
 Heatr7a 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
716VRSDVFRKSTGIFSIubiquitination[1]
725TGIFSIFKDRSEHEVubiquitination[1]
1090RGNVLLEKVPEIVSVubiquitination[1]
1176MSKDVPFKESRAFLLubiquitination[1]
1313QLASSMAKYAGPRLPacetylation[2]
1396MASGSPDKVRAHGPQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1640 AA 
Protein Sequence
MTRPYIKRLS FTLLDSITDK DPMVQEQVCS ALCSLGDAQP DETLHACEEY LRQHDKLAHP 60
YRTKILRAME TVLSSHIHDL DKDTAGAVIL LATSEMTRTK ELDCDWQQAA GSVLVAVGKR 120
FTNQVMEEVL SRFQPGMLPH SSVLHTLANL SVSNAFDMVP FLPSILSTML PMLSMAKQDA 180
LKVVFCGALQ HFSESILEYL ANLDQAPDPT VRKDTFGADI FGAYDVLFHH WLQSRDAKLR 240
LAVVAALGPM SHLLPSERLE EQLPKLLPAV LGLYKKHAEA FQISKSLGQI LEAAVNVSSR 300
TLEVQLDALL VALHAQICVP VESSSPLVMN SQKEVLRCFT VLACCSPDRL LAFLLPRLDT 360
SNERLRVGTL QILRHIINSA AAQMEAKQPF ILSSMRLPLL DTNDKVKRAV VQVISAMAHH 420
GYLEQPGGEV MVEYIVQQCA LPAEEPEKPG PDGEDLAADS VRAVSIRTLY LVSTTVDRMN 480
SVLWPYLLEF LTPVRFTAAL TPLCRSLVHL ALKRQEAGAD DFLIQYNANA NLPSPFAMTT 540
RLLVVSSNPY LGDGRGAASL RLLKVMHQNI HPFLGQRWET TMPMLLEYLD EHTEESLSLK 600
EWEEKLLMFL RDTLAVVSDN IWICQLSQEM CKQLPSYSGT PQEKNFLYKC IGTTLGAASS 660
KEVVRKHLRE LLETARYQEE AEQEGLACCF GICAITHLED TLAQLEDFVR SDVFRKSTGI 720
FSIFKDRSEH EVERMKSCLI LCYGHVAAQA PRELVLARVE SDILRSMFQC FNTKVLGIKV 780
ETKDPALKLC LVQSLCMVSQ AMCSSAQASS FHFLRKTELV TQMMEFIRAE PPDCLRTPIR 840
KKAMLACTYL VNLEPALEEQ TQADVVHSCL HSVMALPPEA EGGDGVGREP LYLDTVCALE 900
DLLTRLLRQN MTPQGLQIMV EHLSPWIKSP RGHERARALG LGACLLEFFQ EHLLVSTLVP 960
FHNLGLLVGL FAPRCADTWT TTRQKAVGCV YSLLYLQLGY EGFSRDHRDD VAERLLTLQD 1020
GLVNADPTIL FHTCHSIAQV IAKRLPSDQL ISLLLTVFES LGDPDKNCSR AATVMINCLL 1080
KERGNVLLEK VPEIVSVLRA KLRDTQEEHV LPAAQHSVYL LASQHCEAVV SSLLGSPLPF 1140
DSHTCALWRA LAVEPGLTAQ VLELLLEKMS KDVPFKESRA FLLGSTADRV ATLLPLAATC 1200
ALYEVLSAPS SGTVVLELYP QLFAALLLRV SCTVGVQLPR NLQAKERRST SPARAARNLD 1260
PCSSAVDALQ ALLLRSGSQD MLRCVELERG WELLKTSAGH EDGVAQLASS MAKYAGPRLP 1320
PVTKALACTQ NSVYEIQRVT STAFLAELLS SNVVNDLMLL EPLLDNLTAR LKDSSASVRR 1380
LVLRGLANMA SGSPDKVRAH GPQLLTAMVS GLDDGDEPHS PVALEAMVGL SRLLDLVEPW 1440
DLRLVLLHTT IRIRPFFDSE KVEFRTASIR LFGHLNKACH GDCEDVFLEQ VVGGLVPLLL 1500
HLRDPQVPVA SACKFALCMC VPHLECAELA AAFYKYLQEG RSVHFGEFLN STCKHLMHHF 1560
PDLLGRLVST NLFYFKSSWD DVRAAAPMFT GFLVLHAEPE QKTQVDLEQL IVALQLLLKD 1620
PVPGVREKAA ETLGRLVKFA 1640 
Gene Ontology
  
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR000357; HEAT.
 IPR021133; HEAT_type_2. 
Pfam
 PF02985; HEAT 
SMART
  
PROSITE
 PS50077; HEAT_REPEAT 
PRINTS