CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025780
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MKIAA4025 protein 
Protein Synonyms/Alias
  
Gene Name
 Hspa4 
Gene Synonyms/Alias
 mKIAA4025 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
132ACVSFGPKNRSIGAAubiquitination[1]
149SQVISNAKNTVQGFKubiquitination[1]
212VTAMLLSKLKETAESubiquitination[1]
214AMLLSKLKETAESVLubiquitination[1]
223TAESVLKKPVVDCVVubiquitination[1]
282DLPALEEKPRNVVFVubiquitination[1]
323DTTLGGRKFDEVLVNubiquitination[1]
393SGTMNRGKFLEMCDDubiquitination[1]
417RSVLEQSKLKKEDIYubiquitination[1]
476AILSPAFKVREFSITubiquitination[1]
518NHAAPFSKVLTFYRKubiquitination[1]
663QAKKAKVKTSTVDLPubiquitination[1]
693LYTENEGKMIMQDKLubiquitination[1]
708EKERNDAKNAVEEYVubiquitination[1]
721YVYEMRDKLSGEYEKubiquitination[1]
728KLSGEYEKFVSEDDRubiquitination[1]
764PKQVYVDKLAELKSLubiquitination[1]
769VDKLAELKSLGQPIKubiquitination[1]
776KSLGQPIKTRFQESEubiquitination[1]
794KLFEELGKQIQQYMKubiquitination[1]
801KQIQQYMKVISSFKNubiquitination[1]
807MKVISSFKNKEDQYEubiquitination[1]
809VISSFKNKEDQYEHLubiquitination[1]
844SKLNLQNKQSLTVDPubiquitination[1]
863KEIEAKIKELTSICSubiquitination[1]
875ICSPIISKPKPKVEPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Nucleotide-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 930 AA 
Protein Sequence
REPSRSSPPP RPAPPLRPWS RSRGPSGRGP RLSPSPKPPS GRSSGFARPA AALHRPTRLA 60
LFHAPTPPGS VCSVGGRPWA RAGAVAGAMS VVGIDLGFQS CYVAVARAGG IETIANEYSD 120
RCTPACVSFG PKNRSIGAAA KSQVISNAKN TVQGFKRFHG RAFSDPFVEA EKSNLAYDIV 180
QLPTGLTGIK VTYMEEERNF TTEQVTAMLL SKLKETAESV LKKPVVDCVV SVPSFYTDAE 240
RRSVMDATQI AGLNCLRLMN ETTAVALAYG IYKQDLPALE EKPRNVVFVD MGHSAYQVSV 300
CAFNKGKLKV LATAFDTTLG GRKFDEVLVN HFCEEFGKKY KLDIKSKIRA LLRLSQECEK 360
LKKLMSANAS DLPLSIECFM NDIDVSGTMN RGKFLEMCDD LLARVEPPLR SVLEQSKLKK 420
EDIYAVEIVG GATRIPAVKE KISKFFGKEL STTLNADEAV TRGCALQCAI LSPAFKVREF 480
SITDVVPYPI SLRWNSPAEE GLSDCEVFPK NHAAPFSKVL TFYRKEPFTL EAYYSSPQDL 540
PYPDPAIAQF SVQKVTPQSD GSSSKVKVKV RVNVHGIFSV SSAALVEVHK SEESEEPMET 600
DQNAKEEEKM QVDQEEPHTE EQQQQPQTPA ENKAESEEME TSQAGSKDKK TDQPPQAKKA 660
KVKTSTVDLP IESQLLWQLD REMLGLYTEN EGKMIMQDKL EKERNDAKNA VEEYVYEMRD 720
KLSGEYEKFV SEDDRNTFTL KLEDTENWLY EDGEDQPKQV YVDKLAELKS LGQPIKTRFQ 780
ESEERPKLFE ELGKQIQQYM KVISSFKNKE DQYEHLDAAD VTKVEKSTNE AMEWMNSKLN 840
LQNKQSLTVD PVVKTKEIEA KIKELTSICS PIISKPKPKV EPPKEEPKHA EQNGPVDGQG 900
DNPGSQAAEH GADTAVPSDG DKKLPEMDID 930 
Gene Ontology
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0051131; P:chaperone-mediated protein complex assembly; IEA:Compara.
 GO:0045040; P:protein import into mitochondrial outer membrane; IEA:Compara. 
Interpro
 IPR018181; Heat_shock_70_CS.
 IPR013126; Hsp_70_fam. 
Pfam
 PF00012; HSP70 
SMART
  
PROSITE
 PS00329; HSP70_2
 PS01036; HSP70_3 
PRINTS
 PR00301; HEATSHOCK70.