CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001181
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transforming acidic coiled-coil-containing protein 1 
Protein Synonyms/Alias
 Gastric cancer antigen Ga55; Taxin-1 
Gene Name
 TACC1 
Gene Synonyms/Alias
 KIAA1103 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
783LERALQQKNQEIEELubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
 Likely involved in the processes that promote cell division prior to the formation of differentiated tissues. 
Sequence Annotation
 DOMAIN 215 297 SPAZ 1.
 DOMAIN 359 507 SPAZ 2.
 REGION 2 55 Interaction with LSM7 and SNRPG.
 REGION 152 259 Interaction with TDRD7.
 REGION 206 427 Interaction with YEATS4.
 REGION 701 805 Interaction with CH-TOG.
 MOTIF 226 241 Bipartite nuclear localization signal 1
 MOTIF 455 471 Bipartite nuclear localization signal 2
 MOD_RES 2 2 N-acetylalanine.
 MOD_RES 4 4 Phosphoserine.
 MOD_RES 10 10 Phosphoserine.
 MOD_RES 228 228 Phosphoserine; by AURKC.
 MOD_RES 276 276 Phosphoserine.
 MOD_RES 406 406 Phosphoserine (By similarity).
 MOD_RES 533 533 Phosphotyrosine.  
Keyword
 Acetylation; Alternative splicing; Cell cycle; Cell division; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 805 AA 
Protein Sequence
MAFSPWQILS PVQWAKWTWS AVRGGAAGED EAGGPEGDPE EEDSQAETKS LSFSSDSEGN 60
FETPEAETPI RSPFKESCDP SLGLAGPGAK SQESQEADEQ LVAEVVEKCS SKTCSKPSEN 120
EVPQQAIDSH SVKNFREEPE HDFSKISIVR PFSIETKDST DISAVLGTKA AHGCVTAVSG 180
KALPSSPPDA LQDEAMTEGS MGVTLEASAE ADLKAGNSCP ELVPSRRSKL RKPKPVPLRK 240
KAIGGEFSDT NAAVEGTPLP KASYHFSPEE LDENTSPLLG DARFQKSPPD LKETPGTLSS 300
DTNDSGVELG EESRSSPLKL EFDFTEDTGN IEARKALPRK LGRKLGSTLT PKIQKDGISK 360
SAGLEQPTDP VARDGPLSQT SSKPDPSQWE SPSFNPFGSH SVLQNSPPLS SEGSYHFDPD 420
NFDESMDPFK PTTTLTSSDF CSPTGNHVNE ILESPKKAKS RLITSGCKVK KHETQSLALD 480
ACSRDEGAVI SQISDISNRD GHATDEEKLA STSCGQKSAG AEVKGEPEED LEYFECSNVP 540
VSTINHAFSS SEAGIEKETC QKMEEDGSTV LGLLESSAEK APVSVSCGGE SPLDGICLSE 600
SDKTAVLTLI REEIITKEIE ANEWKKKYEE TRQEVLEMRK IVAEYEKTIA QMIEDEQRTS 660
MTSQKSFQQL TMEKEQALAD LNSVERSLSD LFRRYENLKG VLEGFKKNEE ALKKCAQDYL 720
ARVKQEEQRY QALKIHAEEK LDKANEEIAQ VRTKAKAESA ALHAGLRKEQ MKVESLERAL 780
QQKNQEIEEL TKICDELIAK LGKTD 805 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.
 GO:0015630; C:microtubule cytoskeleton; IDA:HPA.
 GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0021987; P:cerebral cortex development; IEA:Compara.
 GO:0022027; P:interkinetic nuclear migration; IEA:Compara.
 GO:0000226; P:microtubule cytoskeleton organization; IEA:Compara.
 GO:0022008; P:neurogenesis; IEA:Compara.
 GO:0032886; P:regulation of microtubule-based process; IEA:Compara. 
Interpro
 IPR007707; TACC. 
Pfam
 PF05010; TACC 
SMART
  
PROSITE
  
PRINTS