CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008584
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Oligomycin resistance ATP-dependent permease YOR1 
Protein Synonyms/Alias
  
Gene Name
 YOR1 
Gene Synonyms/Alias
 YGR281W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
527PSPGFDPKLALKMTHubiquitination[1]
598DGPEDLEKTSFRGFKubiquitination[1]
838LKYESEVKELTELKKubiquitination[1]
846ELTELKKKATEMSQTubiquitination[1]
858SQTANSGKIVADGHTubiquitination[1]
1238KNLNLNIKSGEKIGIubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Required for oligomycin resistance. 
Sequence Annotation
 DOMAIN 207 493 ABC transmembrane type-1 1.
 DOMAIN 581 808 ABC transporter 1.
 DOMAIN 897 1175 ABC transmembrane type-1 2.
 DOMAIN 1213 1464 ABC transporter 2.
 NP_BIND 621 628 ATP 1 (Potential).
 NP_BIND 1247 1254 ATP 2 (Potential).
 MOD_RES 24 24 Phosphoserine.
 MOD_RES 53 53 Phosphothreonine.
 CARBOHYD 661 661 N-linked (GlcNAc...) (Potential).
 CARBOHYD 759 759 N-linked (GlcNAc...) (Potential).
 CARBOHYD 799 799 N-linked (GlcNAc...) (Potential).  
Keyword
 ATP-binding; Complete proteome; Glycoprotein; Membrane; Nucleotide-binding; Phosphoprotein; Reference proteome; Repeat; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1477 AA 
Protein Sequence
MTITVGDAVS ETELENKSQN VVLSPKASAS SDISTDVDKD TSSSWDDKSL LPTGEYIVDR 60
NKPQTYLNSD DIEKVTESDI FPQKRLFSFL HSKKIPEVPQ TDDERKIYPL FHTNIISNMF 120
FWWVLPILRV GYKRTIQPND LFKMDPRMSI ETLYDDFEKN MIYYFEKTRK KYRKRHPEAT 180
EEEVMENAKL PKHTVLRALL FTFKKQYFMS IVFAILANCT SGFNPMITKR LIEFVEEKAI 240
FHSMHVNKGI GYAIGACLMM FVNGLTFNHF FHTSQLTGVQ AKSILTKAAM KKMFNASNYA 300
RHCFPNGKVT SFVTTDLARI EFALSFQPFL AGFPAILAIC IVLLIVNLGP IALVGIGIFF 360
GGFFISLFAF KLILGFRIAA NIFTDARVTM MREVLNNIKM IKYYTWEDAY EKNIQDIRTK 420
EISKVRKMQL SRNFLIAMAM SLPSIASLVT FLAMYKVNKG GRQPGNIFAS LSLFQVLSLQ 480
MFFLPIAIGT GIDMIIGLGR LQSLLEAPED DPNQMIEMKP SPGFDPKLAL KMTHCSFEWE 540
DYELNDAIEE AKGEAKDEGK KNKKKRKDTW GKPSASTNKA KRLDNMLKDR DGPEDLEKTS 600
FRGFKDLNFD IKKGEFIMIT GPIGTGKSSL LNAMAGSMRK TDGKVEVNGD LLMCGYPWIQ 660
NASVRDNIIF GSPFNKEKYD EVVRVCSLKA DLDILPAGDM TEIGERGITL SGGQKARINL 720
ARSVYKKKDI YLFDDVLSAV DSRVGKHIMD ECLTGMLANK TRILATHQLS LIERASRVIV 780
LGTDGQVDIG TVDELKARNQ TLINLLQFSS QNSEKEDEEQ EAVVAGELGQ LKYESEVKEL 840
TELKKKATEM SQTANSGKIV ADGHTSSKEE RAVNSISLKI YREYIKAAVG KWGFIALPLY 900
AILVVGTTFC SLFSSVWLSY WTENKFKNRP PSFYMGLYSF FVFAAFIFMN GQFTILCAMG 960
IMASKWLNLR AVKRILHTPM SYIDTTPLGR ILNRFTKDTD SLDNELTESL RLMTSQFANI 1020
VGVCVMCIVY LPWFAIAIPF LLVIFVLIAD HYQSSGREIK RLEAVQRSFV YNNLNEVLGG 1080
MDTIKAYRSQ ERFLAKSDFL INKMNEAGYL VVVLQRWVGI FLDMVAIAFA LIITLLCVTR 1140
AFPISAASVG VLLTYVLQLP GLLNTILRAM TQTENDMNSA ERLVTYATEL PLEASYRKPE 1200
MTPPESWPSM GEIIFENVDF AYRPGLPIVL KNLNLNIKSG EKIGICGRTG AGKSTIMSAL 1260
YRLNELTAGK ILIDNVDISQ LGLFDLRRKL AIIPQDPVLF RGTIRKNLDP FNERTDDELW 1320
DALVRGGAIA KDDLPEVKLQ KPDENGTHGK MHKFHLDQAV EEEGSNFSLG ERQLLALTRA 1380
LVRQSKILIL DEATSSVDYE TDGKIQTRIV EEFGDCTILC IAHRLKTIVN YDRILVLEKG 1440
EVAEFDTPWT LFSQEDSIFR SMCSRSGIVE NDFENRS 1477 
Gene Ontology
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0005886; C:plasma membrane; IDA:SGD.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0008559; F:xenobiotic-transporting ATPase activity; TAS:SGD. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR017940; ABC_transporter_type1.
 IPR001140; ABC_transptr_TM_dom.
 IPR011527; ABC_transptrTM_dom_typ1.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00664; ABC_membrane
 PF00005; ABC_tran 
SMART
 SM00382; AAA 
PROSITE
 PS50929; ABC_TM1F
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS