CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040850
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Syntaxin-3 
Protein Synonyms/Alias
  
Gene Name
 STX3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
69NKLKSMEKHIEEDEVubiquitination[1, 2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Coiled coil; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 258 AA 
Protein Sequence
MDEFFSEIEE TRLNIDKISE HVEEAKKLYS IILSAPIPEP KTKDDLEQLT TEIKKRANNV 60
RNKLKSMEKH IEEDEVRSSA DLRIRKSQHS VLSRKFVEVM TKYNEAQVDF RERSKGRIQR 120
QLEITGKKTT DEELEEMLES GNPAIFTSGI IDSQISKQAL SEIEGRHKDI VRLESSIKEL 180
HDMFMDIAML VENQGEMLDN IELNVMHTVD HVEKARDETK KAVKYQSQAR KKLIIIIVLV 240
VVLLGILALI IGLSVGLN 258 
Gene Ontology
 GO:0016324; C:apical plasma membrane; IEA:Compara.
 GO:0030426; C:growth cone; IEA:Compara.
 GO:0030141; C:secretory granule; IEA:Compara.
 GO:0031201; C:SNARE complex; IEA:Compara.
 GO:0050544; F:arachidonic acid binding; IEA:Compara.
 GO:0006944; P:cellular membrane fusion; IEA:Compara.
 GO:0006887; P:exocytosis; IEA:Compara.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0031175; P:neuron projection development; IEA:Compara.
 GO:0006836; P:neurotransmitter transport; IEA:InterPro. 
Interpro
 IPR015708; Syntaxin-3.
 IPR006012; Syntaxin/epimorphin_CS.
 IPR006011; Syntaxin_N.
 IPR010989; t-SNARE.
 IPR000727; T_SNARE_dom. 
Pfam
 PF05739; SNARE
 PF00804; Syntaxin 
SMART
 SM00503; SynN
 SM00397; t_SNARE 
PROSITE
 PS00914; SYNTAXIN
 PS50192; T_SNARE 
PRINTS