CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038838
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Voltage-dependent R-type calcium channel subunit alpha-1E 
Protein Synonyms/Alias
  
Gene Name
 Cacna1e 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
41SGPAAAYKQSKAQRAubiquitination[1]
1088PLKEAETKEEEEEVEubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
  
Sequence Annotation
  
Keyword
 Calcium; Calcium channel; Calcium transport; Complete proteome; Ion channel; Ion transport; Membrane; Reference proteome; Transmembrane; Transport; Voltage-gated channel. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2296 AA 
Protein Sequence
MARFGEAVVV GRPGSGDGDS DQSRNRQGTP VPASGPAAAY KQSKAQRART MALYNPIPVR 60
QNCFTVNRSL FIFGEDNIVR KYAKKLIDWP PFEYMILATI IANCIVLALE QHLPEDDKTP 120
MSRRLEKTEP YFIGIFCFEA GIKIVALGFI FHKGSYLRNG WNVMDFIVVL SGILATAGTH 180
FNTHVDLRTL RAVRVLRPLK LVSGIPSLQI VLKSIMKAMV PLLQIGLLLF FAILMFAIIG 240
LEFYSGKLHR ACFMNNSGIL EGFDPPHPCG VQGCPAGYEC KDWIGPNDGI TQFDNILFAV 300
LTVFQCITME GWTTVLYNTN DALGATWNWL YFIPLIIIGS FFVLNLVLGV LSGEFAKERE 360
RVENRRAFMK LRRQQQIERE LNGYRAWIDK AEEVMLAEEN KNSGTSALEV LRRATIKRSR 420
TEAMTRDSSD EHCVDISSVG TPLARASIKS TKVDGASYFR HKERLLRISI RHMVKSQVFY 480
WIVLSVVALN TACVAIVHHN QPQWLTHLLY YAEFLFLGLF LLEMSLKMYG MGPRLYFHSS 540
FNCFDFGVTV GSIFEVVWAI FRPGTSFGIS VLRALRLLRI FKITKYWASL RNLVVSLMSS 600
MKSIISLLFL LFLFIVVFAL LGMQLFGGRF NFNDGTPSAN FDTFPAAIMT VFQILTGEDW 660
NEVMYNGIRS QGGVSSGMWS AIYFIVLTLF GNYTLLNVFL AIAVDNLANA QELTKDEQEE 720
EEAFNQKHAL QKAKEVSPMS APNMPSIERE RRRRHHMSVW EQRTSQLRRH MQMSSQEALN 780
KEEAPPMNPL NPLNPLSPLN PLNAHPSLYR RPRPIEGLAL GLGLEKCEEE RISRGGSLKG 840
DIGGLTSVLD NQRSPLSLGK REPPWLPRSC HGNCDPTQQE TGGGETVVTF EDRARHRQSQ 900
RRSRHRRVRT EGKESASASR SRSASQERSL DEGVSIDGEK EHEPQSSHRS KEPTIHEEER 960
TQDLRRTNSL MVPRGSGLVG ALDEAETPLV QPQPELEVGK DAALTEQEAE GSSEQALLAD 1020
VQLDVGRGIS QSEPDLSCMT TNMDKATTES TSVTVAIPDM DPLVDSTVVN ISNKTDGEAS 1080
PLKEAETKEE EEEVEKKKQK KEKRETGKAM VPHSSMFIFS TTNPIRKACH YIVNLRYFEM 1140
CILLVIAASS IALAAEDPVL TNSERNKVLR YFDYVFTGVF TFEMVIKMID QGLILQDGSY 1200
FRDLWNILDF VVVVGALVAF ALANNLKTNK GRDIKTIKSL RVLRVLRPLK TIKRLPKLKA 1260
VFDCVVTSLK NVFNILIVYK LFMFIFAVIA VQLFKGKFFY CTDSSKDTEK ECIGNYVDHE 1320
KNKMEVKGRE WKRHEFHYDN IIWALLTLFT VSTGEGWPQV LQHSVDVTEE DRGPSRSNRM 1380
EMSIFYVVYF VVFPFFFVNI FVALIIITFQ EQGDKMMEEC SLEKNERACI DFAISAKPLT 1440
RYMPQNRHTF QYRVWHFVVS PSFEYTIMAM IALNTVVLMM KYYSAPWTYE LALKYLNIAF 1500
TMVFSLECVL KVIAFGFLNY FRDTWNIFDF ITVIGSITEI ILTDSKLVNT SGFNMSFLKL 1560
FRAARLIKLL RQGYTIRILL WTFVQSFKAL PYVCLLIAML FFIYAIIGMQ VFGNIKLDEE 1620
SHINRHNNFR SFFGSLMLLF RSATGEAWQE IMLSCLGEKG CEPDTTAPSG QNESERCGTD 1680
LAYVYFVSFI FFCSFLMLNL FVAVIMDNFE YLTRDSSILG PHHLDEFVRV WAEYDRAACG 1740
RIHYTEMYEM LTLMSPPLGL GKRCPSKVAY KRLVLMNMPV AEDMTVHFTS TLMALIRTAL 1800
DIKIAKGGAD RQQLDSELQK ETLAIWPHLS QKMLDLLVPM PKASDLTVGK IYAAMMIMDY 1860
YKQSKVKKQR QQLEEQKNAP MFQRMEPSSL PQEIISNAKA LPYLQQDPVS GLSGRSGYPS 1920
MSPLSPQEIF QLACMDPADD GQFQEQQSLE PEVSELKSVQ SSNHGIYLPP DTQEHAGSGR 1980
ASSMPRLTMD PQVVTDPSSM RRSFSTIRDK RSNSSWLEEF SMERSSENTY KSRRRSYHSS 2040
LRLSAHRLNS DSGHKSDTHR SGGRERGRSK ERKHLLSPDV SRCNSEERGT QADWESPERR 2100
QSRSPSEGRS QTPNRQGTGS LSESSIPSIS DTSTPRRSRR QLPPVPPKPR PLLSYSSLMR 2160
HTGGISPPPD GSEGGSPLAS QALESNSACL TESSNSLHPQ QGQHPSPQHY ISEPYLALHE 2220
DSHASDCGEE ETLTFEAAVA TSLGRSNTIG SAPPLRHSWQ MPNGHYRRRR RGGPGPGMMC 2280
GAVSDLLSDT EEDDKC 2296 
Gene Ontology
 GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro. 
Interpro
 IPR002048; EF_hand_dom.
 IPR005821; Ion_trans_dom.
 IPR027359; K_channel_four-helix_dom.
 IPR014873; VDCC_a1su_IQ.
 IPR005449; VDCC_R_a1su.
 IPR002077; VDCCAlpha1. 
Pfam
 PF08763; Ca_chan_IQ
 PF00520; Ion_trans 
SMART
 SM01062; Ca_chan_IQ 
PROSITE
 PS50222; EF_HAND_2 
PRINTS
 PR00167; CACHANNEL.
 PR01633; RVDCCALPHA1.