CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014728
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glycosyltransferase 8 domain-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 GLT8D1 
Gene Synonyms/Alias
 GALA4A; AD-017; MSTP137; UNQ572/PRO1134 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
119WLNSDSLKSIRYKIVubiquitination[1]
165PILVPSAKKAIYMDDubiquitination[1]
166ILVPSAKKAIYMDDDubiquitination[1]
189ALYNTALKPGHAAAFacetylation[2]
206DCDSASTKVVIRGAGacetylation[2]
225YIGYLDYKKERIRKLacetylation[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786
Functional Description
  
Sequence Annotation
 CARBOHYD 249 249 N-linked (GlcNAc...).
 CARBOHYD 257 257 N-linked (GlcNAc...) (Potential).  
Keyword
 Alternative splicing; Complete proteome; Glycoprotein; Glycosyltransferase; Membrane; Polymorphism; Reference proteome; Signal-anchor; Transferase; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 371 AA 
Protein Sequence
MSFRKVNIII LVLAVALFLL VLHHNFLSLS SLLRNEVTDS GIVGPQPIDF VPNALRHAVD 60
GRQEEIPVVI AASEDRLGGA IAAINSIQHN TRSNVIFYIV TLNNTADHLR SWLNSDSLKS 120
IRYKIVNFDP KLLEGKVKED PDQGESMKPL TFARFYLPIL VPSAKKAIYM DDDVIVQGDI 180
LALYNTALKP GHAAAFSEDC DSASTKVVIR GAGNQYNYIG YLDYKKERIR KLSMKASTCS 240
FNPGVFVANL TEWKRQNITN QLEKWMKLNV EEGLYSRTLA GSITTPPLLI VFYQQHSTID 300
PMWNVRHLGS SAGKRYSPQF VKAAKLLHWN GHLKPWGRTA SYTDVWEKWY IPDPTGKFNL 360
IRRYTEISNI K 371 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005739; C:mitochondrion; IDA:HPA.
 GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW. 
Interpro
 IPR002495; Glyco_trans_8. 
Pfam
 PF01501; Glyco_transf_8 
SMART
  
PROSITE
  
PRINTS