CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011351
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ATP synthase lipid-binding protein, mitochondrial 
Protein Synonyms/Alias
 ATP synthase proteolipid P2; ATPase protein 9; ATPase subunit c 
Gene Name
 ATP5G2 
Gene Synonyms/Alias
 PSEC0033 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
31PLSAVVLKRPEILTDubiquitination[1]
Reference
 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094
Functional Description
 Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element. 
Sequence Annotation
  
Keyword
 Alternative splicing; CF(0); Complete proteome; Hydrogen ion transport; Ion transport; Lipid-binding; Membrane; Mitochondrion; Polymorphism; Reference proteome; Transit peptide; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 141 AA 
Protein Sequence
MFACSKFVST PSLVKSTSQL LSRPLSAVVL KRPEILTDES LSSLAVSCPL TSLVSSRSFQ 60
TSAISRDIDT AAKFIGAGAA TVGVAGSGAG IGTVFGSLII GYARNPSLKQ QLFSYAILGF 120
ALSEAMGLFC LMVAFLILFA M 141 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005753; C:mitochondrial proton-transporting ATP synthase complex; TAS:ProtInc.
 GO:0045263; C:proton-transporting ATP synthase complex, coupling factor F(o); IEA:UniProtKB-KW.
 GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
 GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
 GO:0005215; F:transporter activity; NAS:ProtInc.
 GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
 GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro.
 GO:0045471; P:response to ethanol; IEA:Compara. 
Interpro
 IPR000454; ATPase_F0-cplx_csu.
 IPR020537; ATPase_F0-cplx_csu_DDCD_BS.
 IPR002379; ATPase_proteolipid_c_like_dom. 
Pfam
 PF00137; ATP-synt_C 
SMART
  
PROSITE
 PS00605; ATPASE_C 
PRINTS
 PR00124; ATPASEC.