| Tag | Content |
|---|
| CPLM ID | CPLM-001697 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Growth arrest-specific protein 8 |
Protein Synonyms/Alias | GAS-8; Growth arrest-specific protein 11; GAS-11 |
Gene Name | GAS8 |
Gene Synonyms/Alias | GAS11 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 285 | RLADPLQKAREEMSE | ubiquitination | [1] | | 363 | VQQKTGFKNLVLERK | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Cytoskeletal linker which binds microtubules and probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility (By similarity). |
Sequence Annotation | REGION 1 114 Regulates microtubule-binding (By
REGION 115 258 Microtubule-binding. |
Keyword | Cell projection; Cilium; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Flagellum; Golgi apparatus; Microtubule; Polymorphism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 478 AA |
Protein Sequence | MAPKKKGKKG KAKGTPIVDG LAPEDMSKEQ VEEHVSRIRE ELDREREERN YFQLERDKIH 60
TFWEITRRQL EEKKAELRNK DREMEEAEER HQVEIKVYKQ KVKHLLYEHQ NNLTEMKAEG 120
TVVMKLAQKE HRIQESVLRK DMRALKVELK EQELASEVVV KNLRLKHTEE ITRMRNDFER 180
QVREIEAKYD KKMKMLRDEL DLRRKTELHE VEERKNGQIH TLMQRHEEAF TDIKNYYNDI 240
TLNNLALINS LKEQMEDMRK KEDHLEREMA EVSGQNKRLA DPLQKAREEM SEMQKQLANY 300
ERDKQILLCT KARLKVREKE LKDLQWEHEV LEQRFTKVQQ ERDELYRKFT AAIQEVQQKT 360
GFKNLVLERK LQALSAAVEK KEVQFNEVLA ASNLDPAALT LVSRKLEDVL ESKNSTIKDL 420
QYELAQVCKA HNDLLRTYEA KLLAFGIPLD NVGFKPLETA VIGQTLGQGP AGLVGTPT 478 |
Gene Ontology | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell. GO:0005874; C:microtubule; IDA:UniProtKB. GO:0005932; C:microtubule basal body; IEA:UniProtKB-SubCell. GO:0031514; C:motile cilium; ISS:UniProtKB. GO:0034613; P:cellular protein localization; IEA:Compara. GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc. GO:0030317; P:sperm motility; ISS:UniProtKB. |
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SMART | |
PROSITE | |
PRINTS | |