| Tag | Content |
|---|
| CPLM ID | CPLM-016631 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ubiquitin carboxyl-terminal hydrolase 40 |
Protein Synonyms/Alias | Deubiquitinating enzyme 40; Ubiquitin thioesterase 40; Ubiquitin-specific-processing protease 40 |
Gene Name | Usp40 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 471 | ITQQFQGKESAYMLF | ubiquitination | [1] | | 504 | RVPCHLLKEMDAANI | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | |
Sequence Annotation | ACT_SITE 50 50 Nucleophile (By similarity).
ACT_SITE 305 305 Proton acceptor (By similarity).
MOD_RES 1207 1207 Phosphoserine. |
Keyword | Alternative splicing; Complete proteome; Hydrolase; Phosphoprotein; Protease; Reference proteome; Thiol protease; Ubl conjugation pathway. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1235 AA |
Protein Sequence | MFGNLFEEDY SSVSSSQYGR GKKLKTKGLE PPAPREFTNL SGIRNQGGTC YLSSLLQTLH 60
FTPEFREALF SLGPEELGSL EDKDKPDAKV RIIPLQLQRL FAQLLLLDQE AASTIDLTDS 120
FGWTNDEEMR QHDVQELNRI LFSALETSLV GTSGHDLIHR LYHGTIVNQI VCKECKNISE 180
RQEDFLDLTV AVKNVSGLED ELCNMYVEEE IFDYDNLYHC GTCDRLVKAA KSAKLRKLPP 240
FLTISLLRFN FDFVKCERYK DTSCYTFPLR INLKPFCEQS ELDDMEYMYD LFSVIIHKGG 300
CYGGHYHVYI KDVDHLGNWQ CQEEISDTNV NVKAPQSEEE ANDPLVVLKT ILLQEEANQI 360
PVDQLGQKLL KKTGISWNKK YRKQHGPLRK FLQLHPQIFL LSTDESTVSL LRNHLTQAPS 420
DLQSCEQILH TLASESPGLN DDTSCPHWFD INDSKVHPIR EKDITQQFQG KESAYMLFYR 480
KATLQRPPEA RANPRYRVPC HLLKEMDAAN ILLQMRRAEC DSANSTFELH LHLGPHYRFF 540
NGALHPAVSE TESVWDLTFD KRKTLGDLRQ SIFQLLECWE GDMVLSVAKR VPAGLHVYHT 600
LDGDDLTLCE AEVADGEDIF VWNGVEVGGV QIQTGFDCEP LLLNILHLEL SGEGSKCEQL 660
VESPHVFPAN AEVGAVFTAL GTPAGAILMN SVESADGECW TAVPKEDMKK TFREQGLRNG 720
SLILVQDSDS DNNSLLPKQG RWTNSMNELN WLQVKNFCQS ESEEKQVQIA VTMHTVVFDI 780
RIKAIKELKL MKELAENSCL RPIDRNGKLL CPVPDSSTLE EAEVKMGSSV GLCLGKAPTS 840
SQLFLFFALG TDIHPGAEMD IIVEETLSVR DCLKIMLEKS GQQGEIWHLR KMDWCYEAGE 900
PLCEEDATLK ELMIRSGDTL LLTEGKLPPP GHLKMPIWWY QPARLSGHCE SRDHLNCAFS 960
QDSTWRAAPT QGAPGPEPAE VSLLYLGDME ISEEATLVEL KSQALALPSV SKLAVQSTAL 1020
LRVWTVESKR PSRLLRTNWR QLKEYRLGRR AELCLELLQK EEDLGPRDVL LRTQLRIPGE 1080
RAYSLATDLI WDTTRGWTAG SLRQRVADFY SLPVEKIEIA KYFPEKFEWL PISSWNQQVA 1140
KRKKKKNQDT LQGGPYYLKD GDTIGIKNLL FDDNDDFSTI RDDIGKENQK RLALEKKKSR 1200
EVHRAQSSDL FSNAGVPARF RGPEASLSIH VASFR 1235 |
Gene Ontology | GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW. GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro. GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |