UniProt Accession

 F7ALS6_MOUSE; F7ALS6 

Genbank Protein ID

 AC138790; AC140375 

Genbank Nucleotide ID

  

Protein Name

 Aspartate aminotransferase, cytoplasmic 

Protein Synonyms/Alias

  

Gene Name

 Got1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
18	WVLPVVRKVEQKIAN	ubiquitination	[1]
92	WYNGTDNKNTPIYVS	ubiquitination	[1]
128	YCYWDAEKRGLDLQG	acetylation	[2]
128	YCYWDAEKRGLDLQG	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 182 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IDA:MGI.
 GO:0004069; F:L-aspartate:2-oxoglutarate aminotransferase activity; IDA:MGI.
 GO:0004609; F:phosphatidylserine decarboxylase activity; IDA:MGI.
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0006532; P:aspartate biosynthetic process; IDA:MGI.
 GO:0055089; P:fatty acid homeostasis; IDA:MGI.
 GO:0019551; P:glutamate catabolic process to 2-oxoglutarate; IDA:MGI.
 GO:0019550; P:glutamate catabolic process to aspartate; IDA:MGI.
 GO:0006114; P:glycerol biosynthetic process; IDA:MGI.
 GO:0006107; P:oxaloacetate metabolic process; IDA:MGI. 

Interpro

 IPR004839; Aminotransferase_I/II.
 IPR000796; Asp_trans.
 IPR015424; PyrdxlP-dep_Trfase.
 IPR015421; PyrdxlP-dep_Trfase_major_sub1. 

Pfam

 PF00155; Aminotran_1_2 

SMART

  

PROSITE

  

PRINTS