CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031640
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Pias4 protein 
Protein Synonyms/Alias
 Protein Pias4; Protein inhibitor of activated STAT, 4 
Gene Name
 Pias4 
Gene Synonyms/Alias
 rCG_29357 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
107DYPVLYGKYLNGLGRacetylation[1]
118GLGRLPTKALKPEVRacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 507 AA 
Protein Sequence
MAAELVEAKN MVMSFRVSDL QMLLGFVGRS KSGLKHELVT RALQLVQFDC SPELFKKIKE 60
LYETRYAKKS AEPGPQAPRP LDPLALHSMP RTPLSGPTVD YPVLYGKYLN GLGRLPTKAL 120
KPEVRLVKLP FFNMLDELLK PTELVPQSAE KLQESPCIFA LTPRQVEMIR NSRELQPGVK 180
AVQVVLRICY SDTSCPQEDQ YPPNIAVKVN HSYCSVPGYY PSNKPGVEPK RPCRPINLTH 240
LMYLSSATNR ITVTWGNYGK SYSVALYLVR QLTSSDLLQR LKTIGVKHPE LCKALVKEKL 300
RLDPDSEIAT TGVRVSLICP LVKMRLSVPC RAETCAHLQC FDAVFYLQMN EKKPTWMCPV 360
CDKPAAYDQL IIDGLLSKIL SECEDADEIE FLAEGSWRPI RAEKEPSCSP QGPILVLGTS 420
DANGLAPASS TPGMGSGLSG PGGAGGGAGA AGGLENGKTG ADVVDLTLDS SSSSEDEDED 480
EDDDEDDDEG PRPKRRCPFQ KGLVPAC 507 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0016363; C:nuclear matrix; IEA:Compara.
 GO:0003677; F:DNA binding; IEA:Compara.
 GO:0019789; F:SUMO ligase activity; IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IEA:Compara.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0043065; P:positive regulation of apoptotic process; IEA:Compara.
 GO:0033235; P:positive regulation of protein sumoylation; IEA:Compara. 
Interpro
 IPR027224; PIAS4.
 IPR023321; PINIT.
 IPR003034; SAP_dom.
 IPR004181; Znf_MIZ. 
Pfam
 PF14324; PINIT
 PF02891; zf-MIZ 
SMART
 SM00513; SAP 
PROSITE
 PS51466; PINIT
 PS50800; SAP
 PS51044; ZF_SP_RING 
PRINTS