CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022139
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter 
Protein Synonyms/Alias
 UDP-GlcA/UDP-GalNAc transporter; Solute carrier family 35 member D1; UDP-galactose transporter-related protein 7; UGTrel7 
Gene Name
 SLC35D1 
Gene Synonyms/Alias
 KIAA0260; UGTREL7 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
350ANNKLDIKGKGAV**ubiquitination[1]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 
Functional Description
 Transports both UDP-glucuronic acid (UDP-GlcA) and UDP- N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to into the endoplasmic reticulum lumen. May participate in glucuronidation and/or chondroitin sulfate biosynthesis. 
Sequence Annotation
  
Keyword
 Complete proteome; Endoplasmic reticulum; Membrane; Polymorphism; Reference proteome; Sugar transport; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 355 AA 
Protein Sequence
MAEVHRRQHA RVKGEAPAKS STLRDEEELG MASAETLTVF LKLLAAGFYG VSSFLIVVVN 60
KSVLTNYRFP SSLCVGLGQM VATVAVLWVG KALRVVKFPD LDRNVPRKTF PLPLLYFGNQ 120
ITGLFSTKKL NLPMFTVLRR FSILFTMFAE GVLLKKTFSW GIKMTVFAMI IGAFVAASSD 180
LAFDLEGYAF ILINDVLTAA NGAYVKQKLD SKELGKYGLL YYNALFMILP TLAIAYFTGD 240
AQKAVEFEGW ADTLFLLQFT LSCVMGFILM YATVLCTQYN SALTTTIVGC IKNILITYIG 300
MVFGGDYIFT WTNFIGLNIS IAGSLVYSYI TFTEEQLSKQ SEANNKLDIK GKGAV 355 
Gene Ontology
 GO:0030176; C:integral to endoplasmic reticulum membrane; NAS:UniProtKB.
 GO:0005461; F:UDP-glucuronic acid transmembrane transporter activity; TAS:Reactome.
 GO:0005463; F:UDP-N-acetylgalactosamine transmembrane transporter activity; NAS:UniProtKB.
 GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
 GO:0030206; P:chondroitin sulfate biosynthetic process; NAS:UniProtKB.
 GO:0048706; P:embryonic skeletal system development; IEA:Compara.
 GO:0006065; P:UDP-glucuronate biosynthetic process; TAS:Reactome.
 GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. 
Interpro
 IPR004853; DUF250. 
Pfam
 PF03151; TPT 
SMART
  
PROSITE
  
PRINTS