CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031835
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DNA ligase 
Protein Synonyms/Alias
  
Gene Name
 TGME49_008580, TGVEG_039790 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
1041HTAGIGEKSPDKGIGacetylation[1]
Reference
 [1] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; DNA damage; DNA recombination; DNA repair; DNA replication; Glycosidase; Hydrolase; Ligase; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1112 AA 
Protein Sequence
MKKAAAVPAK KQTSILSAAT LCLSPSPSVC LGPHATQLLP VAVDMAFASS RLDFPLCRSF 60
LSRKDDTRAP SSTKTGDSRA DATANLLAGL APEESAVPLR KRQLPASAAA FSPSAKKRRE 120
GGCEREETER AEVPQEDARR EAVASLKDQE ACLVEDAPEV IGSDGRRRGR LRKELERDAE 180
NDVNEGNGQS NAATENVETG VHAEAQADRH THTNEDAEDD PVSEAVSDRE SIDSDSSVAS 240
SRDASHPRGD VKKVSASSAA GRRALEMLQK KKRSPGSEKR KAALFSDSED AAAGSMSEDE 300
GRHEASKAKK SVLEALAERK GESREETANE ETRKEKKREA PQEKKSTTRK KKSEDDEQLK 360
TGTLFAVRVL GKDSSADLSS PLFDPAAVPL ASVSAKKSER SSKKEPVDDS PPILFEALVN 420
AFDKIEQMKA SGTGSNKKQT VVLTNLFRLL LFYAPKTLHK AIYICLNKVA PDYLGQEVGV 480
GESLILRAMA ETYGRTEAHL KKELQHIEDL GKIAEQSSCK TRTLFPPPRL TIDGVFDQVK 540
AISQCAGKDS QVHKRELLKR LLVGGKGSEP KYIIRFLQQR MRTGASTATV YQALAFACFL 600
THNARNGRPA IGDTRRYVPS PEETSKDPSS SPSSPSSSPS SSSSSSSSSS SSSSSSSAPL 660
PSSMSAVELE SHLSRMEQSV RRALCEVPNV EVVVGHLLQG ADAEALSSLC VATPGIPLQP 720
MLARPTRGFE EVMERLKQTE FTCEFKYDGE RIQLHLISPT RVRLFSRNLE EITQKYPDVI 780
DMFLASLQPT TEECILDGEV VAYDEENRTI LPFQTLTRRK RKGVEKDGIE VRVALFLFDC 840
MRLNGECLLG KTLEARREKM RQAIDFERSP LVQQAAYKDI RGAQDFEDFL TEAIEGNCEG 900
LMVKTLRENA TYEPSKRSLN WLKVKKDYVD GLTDSVDLVP IGACYGKGKR SGTFGTYLLA 960
VYNPADETFQ TVCKAATGFS EEALQQHHKA LSDRIISHKK PYYDVSPKLE ADVWFEACQV 1020
WECRAADLSI SPVHTAGIGE KSPDKGIGLR FPRFLRVRED KNPEQATTST QIVEMYTNQF 1080
RQNKVHGGRT NAEREEEEVE DESESEEQRK ED 1112 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0003910; F:DNA ligase (ATP) activity; IEA:EC.
 GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
 GO:0051103; P:DNA ligation involved in DNA repair; IEA:InterPro.
 GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
 GO:0006260; P:DNA replication; IEA:UniProtKB-KW. 
Interpro
 IPR000977; DNA_ligase_ATP-dep.
 IPR012309; DNA_ligase_ATP-dep_C.
 IPR012310; DNA_ligase_ATP-dep_cent.
 IPR016059; DNA_ligase_ATP-dep_CS.
 IPR012308; DNA_ligase_ATP-dep_N.
 IPR012340; NA-bd_OB-fold. 
Pfam
 PF04679; DNA_ligase_A_C
 PF01068; DNA_ligase_A_M
 PF04675; DNA_ligase_A_N 
SMART
  
PROSITE
 PS00697; DNA_LIGASE_A1
 PS00333; DNA_LIGASE_A2
 PS50160; DNA_LIGASE_A3 
PRINTS