CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036917
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Syntaxin-binding protein 4 
Protein Synonyms/Alias
  
Gene Name
 STXBP4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
363EAKITELKAQLADYSubiquitination[1]
374ADYSDQNKESVQDLKubiquitination[1]
461ATLALESKELVKSVRubiquitination[2]
465LESKELVKSVRALLDubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 531 AA 
Protein Sequence
MNKNTSTVVS PSLLEKDPAF QMITIAKETG LGLKVLGGIN RNEGPLVYIQ EIIPGGDCYK 60
DGRLKPGDQL VSVNKESMIG VSFEEAKSII TGAKLRLESA WEIAFIRQKS DNIQPENLSC 120
TSLIEASGEY GPQASTLSLF SSPPEILIPK TSSTPKTNND ILSSCEIKTG YNKTVQIPIT 180
SENSTVGLSN TDVASAWTEN YGLQEKISLN PSVRFKAEKL EMALNYLGIQ PTKEQHQALR 240
QQVQADSKGT VSFGDFVQVA RNLFCLQLDE VNVGAHEISN ILDSQLLPCD SSEADEMERL 300
KCERDDALKE VNTLKEAKAV VEETRALRSR IHLAEAAQRQ AHGMEMDYEE VIRLLEAKIT 360
ELKAQLADYS DQNKESVQDL KKRIMVLDCQ LRKSEMARKT FEASTEKLLH FVEAIQEVFS 420
DNSTPLSNLS ERRAVLASQT SLTPLGRNGR SIPATLALES KELVKSVRAL LDMDCLPYGW 480
EEAYTADGIK YFINHVTQTT SWIHPVMSVL NLSRSEENEE DCSRELPNQK S 531 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0005509; F:calcium ion binding; IEA:InterPro. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR001478; PDZ.
 IPR001202; WW_dom. 
Pfam
 PF00595; PDZ
 PF00397; WW 
SMART
 SM00228; PDZ
 SM00456; WW 
PROSITE
 PS50106; PDZ
 PS01159; WW_DOMAIN_1
 PS50020; WW_DOMAIN_2 
PRINTS