CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035013
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
162LLSVDYGKKSKLEFSacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Cytoplasm; Cytoskeleton; GTP-binding; Microtubule; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 445 AA 
Protein Sequence
MRERISILIG QAGVQIGNAC WEYCLERGIQ PDVQMPSDKT IGGGDGSFNT FFSETGAGKH 60
EPRAVFVDLE PTVNDEVYTG TYRQLFHSQP LITGKEDAAN NYARGHYAIG EEIIDLVLDE 120
IRKMADQCTG LQGFLVFHSF GGGTGSGFTS LLMELLSVDY GKKSKLEFSI YPTPTVSTAV 180
VEPYNSILPT HTTLEHSDCA FMVDNEAIYD ICRRNLNTER PTYTNLNRLI GQIVLSIAAS 240
LRFGGVLNAD LAEFQTNQAP YPHIHYAPVV SAEKAYHEQL SVAEITNACF EPANQMVKCD 300
PHHGKYMACC LLYCGDVVPK DVNADIATIK TKRSIQFVDW CPTGFKVGIN YQPPTVVPGG 360
DLARVQRAVC TLNNTTATAE AWAHLDHKFD PMYAKRAFVH WCMGEGMEEG EFSEAREDTA 420
ALEKDYEEVG MDSVEGDSEE EEEEY 445 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
 GO:0007017; P:microtubule-based process; IEA:InterPro.
 GO:0051258; P:protein polymerization; IEA:InterPro. 
Interpro
 IPR002452; Alpha_tubulin.
 IPR008280; Tub_FtsZ_C.
 IPR000217; Tubulin.
 IPR018316; Tubulin/FtsZ_2-layer-sand-dom.
 IPR023123; Tubulin_C.
 IPR017975; Tubulin_CS.
 IPR003008; Tubulin_FtsZ_GTPase. 
Pfam
 PF00091; Tubulin
 PF03953; Tubulin_C 
SMART
 SM00864; Tubulin
 SM00865; Tubulin_C 
PROSITE
 PS00227; TUBULIN 
PRINTS
 PR01162; ALPHATUBULIN.
 PR01161; TUBULIN.