| Tag | Content |
|---|
| CPLM ID | CPLM-020629 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Beta-catenin-like protein 1 |
Protein Synonyms/Alias | Nuclear-associated protein; NAP |
Gene Name | Ctnnbl1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 388 | TIFPLFMKSPRKIKK | acetylation | [1] | | 534 | KIVRHIIKEYAENIG | acetylation | [1] |
|
Reference | [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways. Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y. Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [ PMID: 22826441] |
Functional Description | Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May induce apoptosis (By similarity). Participates in AID/AICDA-mediated Ig class switching recombination (CSR). |
Sequence Annotation | MOTIF 16 33 Nuclear localization signal (By
MOD_RES 91 91 N6-acetyllysine (By similarity).
MOD_RES 389 389 Phosphoserine (By similarity).
MOD_RES 545 545 Phosphoserine. |
Keyword | Acetylation; Apoptosis; Complete proteome; Nucleus; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 563 AA |
Protein Sequence | MDVGELLSYQ PNRGTKRPRD DEEEELKTRR KQTGPRERGR YREEEATAAE DTADDKKRLL 60
QIIDRDGEEE EEEEEPLDES SVKKMILTFE KRSYKNQELR IKFPDNPEKF MESELDLNDI 120
IQEMHVVATM PDLYHLLVEL SAVQSLLGLL GHDNTDVSIA VVDLLQELTD IDTLHESEEG 180
AEVLIDALVD GQVAALLVQN LERLDESVRE EADGVHNTLA IVENMAEFRP EMCTEAAQQG 240
LLQWLLKRLK AKMPFDANKL YCSEVLAILL QDNDENRELL GELDGIDVLL QQLSVFKRHN 300
PSTAEEQEMM ENLFDALCSC LMLSSNRERF LKGEGLQLMN LMLREKKVSR SSALKVLDHA 360
MIGPEGTDNC HKFVDILGLR TIFPLFMKSP RKIKKVGTTE KEHEEHVCSI LASLLRNLRG 420
QQRTRLLNKF TENDSEKVDR LMELHFKYLS AMQVADKKIE GEKHDIVRRG EIIDNDMEDE 480
FYLRRLDAGL FILQHICYIM AEICNANVPQ IRQRVHQILN MRGSSIKIVR HIIKEYAENI 540
GDGRSPEFRE TEQKRILALL ENF 563 |
Gene Ontology | GO:0000974; C:Prp19 complex; ISS:UniProtKB. GO:0005681; C:spliceosomal complex; ISS:UniProtKB. GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. GO:0006917; P:induction of apoptosis; ISO:MGI. GO:0016445; P:somatic diversification of immunoglobulins; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |