CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040926
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 AT-rich interactive domain-containing protein 2 
Protein Synonyms/Alias
  
Gene Name
 ARID2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
46KHVMQLEKDPKIITLubiquitination[1, 2]
89RDFVKFWKDIVDDNEubiquitination[1]
126SLFHPPRKLGINDIEubiquitination[1, 2]
222MSRDRFLKMRGMEILubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1639 AA 
Protein Sequence
MDFNSPNDYN KLVLSLLSGL PNEVDFAINV CTLLSNESKH VMQLEKDPKI ITLLLANAGV 60
FDDTLGSFST VFGEEWKEKT DRDFVKFWKD IVDDNEVRDL ISDRNKSHEG TSGEWIWESL 120
FHPPRKLGIN DIEGQRVLQI AVILRNLSFE EGNVKLLAAN RTCLRFLLLS AHSHFISLRQ 180
LGLDTLGNIA AELLLDPVDF KTTHLMFHTV TKCLMSRDRF LKMRGMEILG NLCKAEDNGV 240
LICEYVDQDS YREIICHLTL PDVLLVISTL EVLYMLTEMG DVACTKIAKV EKSIDMLVCL 300
VSMDIQMFGP DALAAVKLIE HPSSSHQMLS EIRPQAIEQV QTQTHVASAP ASRAVVAQHV 360
APPPGIVEID SEKFACQWLN AHFEVNPDCS VSRAEMYSEY LSTCSKLARG GILTSTGFYK 420
CLRTVFPNHT VKRVEDSSSN GQAHIHVVGV KRRAIPLPIQ MYYQQQPVST SVVRVDSVPD 480
VSPAPSPAGI PHGSQTIGNH FQRTPVANQS SNLTATQMSF PVQGVHTVAQ TVSRIPQNPS 540
PHTHQQQNAP VTVIQSKAPI PCEVVKATVI QNSIPQTGVP VSIAVGGGPP QSSVVQNHST 600
GPQPVTVVNS QTLLHHPSVI PQQSPLHTVV PGQIPSGTPV TVIQQAVPQS HMFGRVQNIP 660
ACTSTVSQGQ QLITTSPQPV QTSSQQTSAG SQSQDTVIIA PPQYVTTSAS NIVSATSVQN 720
FQVATGQMVT IAGVPSPQAS RVGFQNIAPK PLPSQQVSST VVQQPIQQPQ QPTQQSVVIV 780
SQPAQQGQTY APAIHQIVLA NPAALPAGQT VQLTGQPNIT PSSSPSPVPA TNNQVPTAMS 840
SSSTPQSQGP PPTVSQMLSV KRQQQQQHSP APPPQQVQVQ VQQPQQVQMQ VQPQQSNAGV 900
GQPASGESSL IKQLLLPKRG PSTPGGKLIL PAPQIPPPNN ARAPSPQVVY QVASNQAAGF 960
GVQGQTPAQQ LLVGQQNVQL VPSAMPPSGG VQTVPISNLQ ILPGPLISNS PATIFQGTSG 1020
NQVTITVVPN TSFAPATVSQ GNATQLIAPA GITMSGTQTG VGLPVQTLPA TQASPAGQSS 1080
CTTATPPFKG DKIICQKEEE AKEATGLHVH ERKIEVMENP SCRRGATNTS NGDTKENEMH 1140
VGSLLNGRKY SDSSLPPSNS GKIQSETNQC SLISNGPSLE LGENGASGKQ NSEQIDMQDI 1200
KSDLRKPLVN GICDFDKGDG SHLSKNIPNH KTSNHVGNGE ISPMEPQGTL DITQQDTAKG 1260
DQLERISNGP VLTLGGSSVS SIQEASNAAT QQFSGTDLLN GPLASSLNSD VPQQRPSVVV 1320
SPHSTTSVIQ GHQIIAVPDS GSKVSHSPAL SSDVRSTNGT AECKTVKRPA EDTDRETVAG 1380
IPNKVGVRIV TISDPNNAGC SATMVAVPAG ADPSTVAKVA IESAVQQKQQ HPPTYVQNVV 1440
PQNTPMPPSP AVQVQGQPNS SQPSPFSGSS QPGDPMRKPG QNFMCLWQSC KKWFQTPSQV 1500
FYHAATEHGG KDVYPGQCLW EGCEPFQRQR FSFITHLQDK HCSKDALLAG LKQDEPGQAG 1560
SQKSSTKQPT VGGTSSTPRA QKAIVNHPSA ALMALRRGSR NLVFRDFTDE KEGPITKHIR 1620
LTAALILKNI GKYSECGRR 1639 
Gene Ontology
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR003150; DNA-bd_RFX.
 IPR011991; WHTH_DNA-bd_dom.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like. 
Pfam
 PF02257; RFX_DNA_binding 
SMART
 SM00355; ZnF_C2H2 
PROSITE
 PS51526; RFX_DBD
 PS00028; ZINC_FINGER_C2H2_1 
PRINTS