UniProt Accession

 J3QSY3_HUMAN; J3QSY3 

Genbank Protein ID

 AL135924; AL583829; AL590311 

Genbank Nucleotide ID

  

Protein Name

 Graves disease carrier protein 

Protein Synonyms/Alias

  

Gene Name

 GDA 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
16	LGVSDSGKIVFLEEA	ubiquitination	[1]
28	EEASQQEKLAKEWCF	ubiquitination	[2]
108	RVVRRTLKNGTTTAC	ubiquitination	[1]
143	GQRAFVGKVCMDLND	ubiquitination	[1]
156	NDTFPEYKETTEESI	ubiquitination	[1]
164	ETTEESIKETERFVS	ubiquitination	[1, 2]
191	RDEVEAVKNLYPSYK	ubiquitination	[3]
198	KNLYPSYKNYTSVYD	ubiquitination	[2, 3]
206	NYTSVYDKNNLLTNK	ubiquitination	[1, 2, 3]
213	KNNLLTNKTVMAHGC	ubiquitination	[1]

Reference

 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 410 AA 

Protein Sequence

Gene Ontology

 GO:0008892; F:guanine deaminase activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006147; P:guanine catabolic process; IEA:InterPro. 

Interpro

 IPR006680; Amidohydro_1.
 IPR014311; Guanine_deaminase. 

Pfam

 PF01979; Amidohydro_1 

SMART

  

PROSITE

  

PRINTS