| Tag | Content |
|---|
| CPLM ID | CPLM-022776 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Calpain-7 |
Protein Synonyms/Alias | PalB homolog; PalBH |
Gene Name | Capn7 |
Gene Synonyms/Alias | Palbh |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 156 | ALSEPLTKPFCKLKS | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Calcium-regulated non-lysosomal thiol-protease (By similarity). |
Sequence Annotation | DOMAIN 232 540 Calpain catalytic.
REGION 541 701 Domain III.
REGION 702 813 Domain N.
ACT_SITE 290 290 By similarity.
ACT_SITE 458 458 By similarity.
ACT_SITE 578 578 By similarity.
MOD_RES 95 95 Phosphothreonine (By similarity). |
Keyword | Complete proteome; Hydrolase; Nucleus; Phosphoprotein; Protease; Reference proteome; Repeat; Thiol protease. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 813 AA |
Protein Sequence | MDASALERDA VQFARLAVQR DHEGRYSEAV FYYKEAAQAL IYAEMAGSSL ERIQEKINEY 60
LERVQALHSA VQSKSTDPLK SKHQLDLERA HFLVTQAFDE DEKGNVEDAI ELYTEAVELC 120
LKTSSETADK TLQNKLKQLA RQALDRAEAL SEPLTKPFCK LKSANMKTKT PPVRTHFPLG 180
PNPFVEKPQA FISPQSCDAQ GQKYTAEEIE VLRTTSKING VEYVPFMSVD LRERFAYPMP 240
FCDRLGKLPL SPKQKTTFSK WVRPEDLTNN PTMIYTVSSF SIKQTIVSDC SFVASLAISA 300
AYERRFNKKL ITSIIYPQNK DGEPEYNPCG KYMVKLHLNG VPRKVIIDDQ LPVDHKGELL 360
CSYSNNKSEL WVSLIEKAYM KVMGGYDFPG SNSNIDLHAL TGWIPERIAM HSDSQTFSKD 420
NSFRMLYQRF HKGDVLITAS TGVMTEAEGE KWGLVPTHAY AVLDIREFKG LRFIQLKNPW 480
SHLRWKGRYS ENDVKNWTPE LQKYLNFDPR TAQKIDNGIF WISWDDLCQY YDVVYLSWNP 540
ALFKESTCIH STWDAKQGPV KDAYSLANNP QYKLEVQCPQ GGAAVWVLLS RHITDKDDFA 600
NNREFITMVV YKTDGKKVYY PADPPPYIDG IRINSPHYLT KIKLTTPGTH TFTLVVSQYE 660
KQNTIHYTVR VYSACSFTFS KIPSPYTLSK RINGKWSGQS AGGCGNFQET HKNNPIYQFH 720
IDKTGPLLIE LRGPRQYSVG FEVVAVSIMG DPGPHGFQRK SSGDYRCGFC YLELENIPAG 780
IFNIIPSTFL PKQEGPFFLD FNSTVPIKTT QLQ 813 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IEA:InterPro. GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |