CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018020
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Coiled-coil alpha-helical rod protein 1 
Protein Synonyms/Alias
 Alpha-helical coiled-coil rod protein; Putative gene 8 protein; Pg8 
Gene Name
 CCHCR1 
Gene Synonyms/Alias
 C6orf18; HCR 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
208RETSLQQKMRLEAQAubiquitination[1]
305TRRAGEAKELAEAQRubiquitination[2]
340TLVENLRKYVGEQVPubiquitination[2]
404QEEELTRKVQPSDSLubiquitination[2]
449LEHSDSVKQLKGQVAubiquitination[2]
452SDSVKQLKGQVASLQubiquitination[2]
479LQRSLQDKAAEVEVEubiquitination[2]
491EVERMGAKGLQLELSubiquitination[2]
570IRGLIARKLALAQLRubiquitination[2]
769LQELERDKNLMLATLubiquitination[2]
800VLPSLLDKKKSVVSSubiquitination[2]
802PSLLDKKKSVVSSPRubiquitination[2]
Reference
 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 May be a regulator of keratinocyte proliferation or differentiation. 
Sequence Annotation
  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Developmental protein; Differentiation; Nucleus; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 782 AA 
Protein Sequence
MWPHSAGARP WASTLTGKDP RVMACWCLDG LPSGLAEPWR ELWRWRSRPL HCVPPFSPLA 60
RSSRDHRNLR RRGNIDGWRQ NLEPSNNVEM FPPSGSTGLI PPSHFQARPL STLPRMAPTW 120
LSDIPLVQPP GHQDVSERRL DTQRPQVTMW ERDVSSDRQE PGRRGRSWGL EGSQALSQQA 180
EVIVRQLQEL RRLEEEVRLL RETSLQQKMR LEAQAMELEA LARAEKAGRA EAEGLRAALA 240
GAEVVRKNLE EGSQRELEEV QRLHQEQLSS LTQAHEEALS SLTSKAEGLE KSLSSLETRR 300
AGEAKELAEA QREAELLRKQ LSKTQEDLEA QVTLVENLRK YVGEQVPSEV HSQTWELERQ 360
KLLETMQHLQ EDRDSLHATA ELLQVRVQSL THILALQEEE LTRKVQPSDS LEPEFTRKCQ 420
SLLNRWREKV FALMVQLKAQ ELEHSDSVKQ LKGQVASLQE KVTSQSQEQA ILQRSLQDKA 480
AEVEVERMGA KGLQLELSRA QEARRRWQQQ TASAEEQLRL VVNAVSSSQI WLETTMAKVE 540
GAAAQLPSLN NRLSYAVRKV HTIRGLIARK LALAQLRQES CPLPPPVTDV SLELQQLREE 600
RNRLDAELQL SARLIQQEVG RAREQGEAER QQLSKVAQQL EQELQQTQES LASLGLQLEV 660
ARQGQQESTE EAASLRQELT QQQELYGQAL QEKVAEVETR LREQLSDTER RLNEARREHA 720
KAVVSLRQIQ RRAAQEKERS QELRRLQEEA RKEEGQRLAR RLQELERDKN LMLATLQQEG 780
LLSRYKQQRL LTVLPSLLDK KKSVVSSPRP PECSASAPVA AAVPTRESIK GSLSVLLDDL 840
QDLSEAISKE EAVCQGDNLD RCSSSNPQMS S 871 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
 GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
 GO:0006611; P:protein export from nucleus; IEA:Compara. 
Interpro
 IPR009800; HCR. 
Pfam
 PF07111; HCR 
SMART
  
PROSITE
  
PRINTS