| Tag | Content |
|---|
| CPLM ID | CPLM-011617 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein-arginine deiminase type-2 |
Protein Synonyms/Alias | Peptidylarginine deiminase II; Protein-arginine deiminase type II |
Gene Name | Padi2 |
Gene Synonyms/Alias | Pdi; Pdi2 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 183 | SDEKVYSKQDLQDMS | ubiquitination | [1] | | 386 | SPRDGNLKDFPIKQL | ubiquitination | [1] | | 582 | IDLPALFKMDENHQA | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Catalyzes the deimination of arginine residues of proteins. |
Sequence Annotation | MOD_RES 1 1 N-acetylmethionine.
MOD_RES 352 352 Citrulline. |
Keyword | Acetylation; Calcium; Citrullination; Complete proteome; Cytoplasm; Direct protein sequencing; Hydrolase; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 673 AA |
Protein Sequence | MQPPIRENML RERTVRLQYG SRVEAVYVLG TQLWTDVYSA APAGAKTFSL KHSEGVKVEV 60
VRDGEAEEVV TNGKQRWALS PSSTLRLSMA QASTEASSDK VTVNYYEEEG SAPIDQAGLF 120
LTAIEISLDV DADRDGEVEK NNPKKASWTW GPEGQGAILL VNCDRDTPWL PKEDCSDEKV 180
YSKQDLQDMS QMILRTKGPD RLPAGYEIVL YISMSDSDKV GVFYVENPFF GQRYIHILGR 240
QKLYHVVKYT GGSAELLFFV EGLCFPDESF SGLVSIHVSL LEYMAEGIPL TPIFTDTVMF 300
RIAPWIMTPN ILPPVSVFVC CMKDNYLFLK EVKNLVEKTN CELKVCFQYM NRGDRWIQDE 360
IEFGYIEAPH KGFPVVLDSP RDGNLKDFPI KQLLGPDFGY VTREPLFETV TSLDSFGNLE 420
VSPPVTVNGK EYPLGRILIG SSFPLSGGRR MTKVVRDFLQ AQQVQAPVEL YSDWLTVGHV 480
DEFMTFIPIP GKKEFRLLMA STSACYQLFR EKQKAGHGEA VMFKGLGGMS SKRITINKIL 540
SNESLTQENQ YFQRCLDWNR DILKRELALT EKDIIDLPAL FKMDENHQAR AFFPNMVNMI 600
VLDKDLGIPK PFGPQVEEEC CLETHVRGLL EPLGLACTFI DDISAYHKFL GEVHCGTNVR 660
RKPFTFKWWH MVP 673 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005509; F:calcium ion binding; IEA:InterPro. GO:0004668; F:protein-arginine deiminase activity; IEA:EC. GO:0018101; P:peptidyl-citrulline biosynthetic process from peptidyl-arginine; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |