UniProt Accession

 Q543N5_MOUSE; Q543N5 

Genbank Protein ID

 AK049191; AK150993; AK152273; AK153432; AK155826; AK159402; AK160856; AK166794; AK169376; AK169834; AK170942; AK171243; AK172026; AK172516; AK172660; CT010279 

Genbank Nucleotide ID

 BAC33601.1; BAE30017.1; BAE31089.1; BAE31990.1; BAE33450.1; BAE35054.1; BAE36049.1; BAE39023.1; BAE41124.1; BAE41399.1; BAE42130.1; BAE42336.1; BAE42784.1; BAE43045.1; BAE43120.1; CAJ18487.1 

Protein Name

 Clic4 protein 

Protein Synonyms/Alias

  

Gene Name

 Clic4 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
11	SMPLNGLKEEDKEPL	ubiquitination	[1]
103	EEVLCPPKYLKLSPK	ubiquitination	[1]
110	KYLKLSPKHPESNTA	ubiquitination	[1]
130	AKFSAYIKNSRPEAN	ubiquitination	[1]
146	ALERGLLKTLQKLDE	ubiquitination	[1]
150	GLLKTLQKLDEYLNS	ubiquitination	[1]
194	ADCNLLPKLHIVKVV	ubiquitination	[1]
199	LPKLHIVKVVAKKYR	ubiquitination	[1]
212	YRNFDIPKGMTGIWR	ubiquitination	[1]
238	TNTCPSDKEVEIAYS	ubiquitination	[1]
249	IAYSDVAKRLTK***	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

  

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 253 AA 

Protein Sequence

Gene Ontology

 GO:0045177; C:apical part of cell; IEA:Compara.
 GO:0009986; C:cell surface; IEA:Compara.
 GO:0005911; C:cell-cell junction; IEA:Compara.
 GO:0005813; C:centrosome; IEA:Compara.
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0005902; C:microvillus; IEA:Compara.
 GO:0030496; C:midbody; IEA:Compara.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0016363; C:nuclear matrix; IEA:Compara.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0005254; F:chloride channel activity; ISO:MGI.
 GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
 GO:0001525; P:angiogenesis; IMP:MGI.
 GO:0048754; P:branching morphogenesis of an epithelial tube; IMP:MGI.
 GO:0071277; P:cellular response to calcium ion; IEA:Compara.
 GO:0001886; P:endothelial cell morphogenesis; IMP:MGI.
 GO:0009566; P:fertilization; IMP:MGI.
 GO:0030216; P:keratinocyte differentiation; IEA:Compara.
 GO:0035264; P:multicellular organism growth; IMP:MGI.
 GO:0030336; P:negative regulation of cell migration; IEA:Compara.
 GO:0061299; P:retina vasculature morphogenesis in camera-type eye; IMP:MGI.
 GO:0007035; P:vacuolar acidification; IMP:MGI. 

Interpro

 IPR010987; Glutathione-S-Trfase_C-like.
 IPR017933; Glutathione_S_Trfase/Cl_chnl_C.
 IPR002946; Int_Cl_channel.
 IPR012336; Thioredoxin-like_fold. 

Pfam

  

SMART

  

PROSITE

 PS50405; GST_CTER 

PRINTS

 PR01263; INTCLCHANNEL.