CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034613
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ankyrin 1, erythroid 
Protein Synonyms/Alias
 Protein Ank1 
Gene Name
 Ank1 
Gene Synonyms/Alias
 rCG_43073 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
63ASKEGHVKMVVELLHubiquitination[1]
1055TVEPRRRKFHRPIGLacetylation[2]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 ANK repeat; Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1707 AA 
Protein Sequence
MAERPRRSGS DPAADAATSF LRAARSGNLD KALDHLRNGV DINTCNQNGL NGLHLASKEG 60
HVKMVVELLH KEIILETTTK VRDGFTPLAV ALQQGHENVV AHLINYGTKG KVRLPALHIA 120
ARNDDTRTAA VLLQNDPNPD VLSKTGFTPL HIAAHYENLN VAQLLLNRGA SVNFTPQNGI 180
TPLHIASRRG NVIMVRLLLD RGAQIETRTK DELTPLHCAA RNGHVRISEI LLDHGAPIQA 240
KTKNGLSPIH MAAQGDHLDC VRLLLQYNAE IDDITLDHLT PLHVAAHCGH HRVAKVLLDK 300
GAKPNSRALN GFTPLHIACK KNHIRVMELL LKTGASIDAV TEKVETPLHM AARAGHTEVA 360
KYLLQNKAKA NAKAKDDQTP LHCAARIGHT SMVKLLLEND ASPNLATTAG HTPLHTAARE 420
GHVDTALALL EKEASQACMT KKGFTPLHVA AKYGKVRLAE LLLEHDAHPN AAGKNGLTPL 480
HVAVHHNNLD IVQLLLPRGG SPHSPAWNGY TPLHIAAKQN QIEVARSLLQ YGGSANAESV 540
QGVTPLHLAA QEGHTEMVAL LLSKQANGNL GNKSGLTPLH LVAQEGHVPV ADVLIKHGVT 600
VDATTRMGYT PLHVASHYGN IKLVKFLLQH QADVNAKTKL GYSPLHQAAQ QGHTDIVTLL 660
LKNGASPNEV SSNGTTPLAI AKRLGYISVT DVLKVVTDET SVVLVSDKHR MSYPETVDEI 720
LDVSEDEGTA HISLTGDELV GSKAERRDSR DVGEEKELLD FVPKLDQVVE SPAIPRIPCV 780
TPETVVIRSE DQEQASKEYD EDSLIPSSPA TETSDNISPV ASPVHTGFLV SFMVDARGGS 840
MRGSRHNGLR VVIPPRTCAA PTRITCRLVK PQKLSTPPPL AEEEGLASRI IALGPTGAQF 900
LSPVIVEIPH FASHGRGDRE LVVLRSENGS VWKEHKSRYG ESYLDQILNG MDEELGSLEE 960
LEKKRVCRII TTDFPLYFVI MSRLCQDYDT IGPEGGSLRS KLVPLVQATF PENAVTKKVK 1020
LALQAQPVPD ELVTKLLGNQ ATFSPIVTVE PRRRKFHRPI GLRIPLPPSW TDNPRDSGEG 1080
DTTSLRLLCS VIGGTDQAQW EDITGTTKLV YANECANFTT NVSARFWLSD CPRTAEAVHF 1140
ATLLYKELTA VPYMAKFVIF AKMNDPREGR LRCYCMTDDK VDKTLEQHEN FVEVARSRDI 1200
EVLEGMPLFA ELSGNLVPVK KAAQQRSFHF QSFRENRLAI PVKVRDSSRE PGGFLSFLRK 1260
PMKYEDAQHI LCHLNVTMPP CTKGSGAEDR RRTLTPLTLR YSILSESRLG FTSDTDRVEM 1320
KMAVIREHLG LSWAVENLYT ALRNIDRSEI VNMLEGSGRQ SRNLKPDRRH GDREYSLSPS 1380
QVNGYSSLQD ELLSPASLHY ALPSPLCADQ YWNEVAVIDA IPLAATEHDT MLEMSDMQVW 1440
SSGLTPSLVT AEDSSLECSK AEDSDAIPEW KLEGAHSEDT QGPELGSQDL VEDDTVDSDA 1500
TNGLADLLGQ QRVHARITDS PSVRQVLDRS QARTVDWYKQ GSAASYPQEA AQSSWQEEVT 1560
QGPQSFQRRI TTIQGPEPGT LQEYEQVVVS TREHVQRGPP ESDSPKAGKD PSLWASESAF 1620
SQEVQGDELQ NIPGEQVTEE QFTDEQGNIV TKKIIRKVVR QVDSSGAIDT QQHEEVELRG 1680
SGLQPDLIEG RKGAQIVKRA SLKRGKQ 1707 
Gene Ontology
 GO:0030673; C:axolemma; IDA:RGD.
 GO:0030863; C:cortical cytoskeleton; IEA:Compara.
 GO:0031430; C:M band; IDA:RGD.
 GO:0005634; C:nucleus; IDA:RGD.
 GO:0045211; C:postsynaptic membrane; IDA:RGD.
 GO:0042383; C:sarcolemma; IDA:RGD.
 GO:0016529; C:sarcoplasmic reticulum; IDA:RGD.
 GO:0014731; C:spectrin-associated cytoskeleton; IEA:Compara.
 GO:0030018; C:Z disc; IDA:RGD.
 GO:0006888; P:ER to Golgi vesicle-mediated transport; IEA:Compara.
 GO:0048821; P:erythrocyte development; IEA:Compara.
 GO:0015672; P:monovalent inorganic cation transport; IEA:Compara.
 GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:Compara.
 GO:0010638; P:positive regulation of organelle organization; IMP:RGD.
 GO:0072661; P:protein targeting to plasma membrane; IEA:Compara. 
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom.
 IPR000906; ZU5. 
Pfam
 PF00023; Ank
 PF12796; Ank_2
 PF00791; ZU5 
SMART
 SM00248; ANK
 SM00218; ZU5 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT
 PS51145; ZU5 
PRINTS
 PR01415; ANKYRIN.