UniProt Accession

 C9JKM9_HUMAN; C9JKM9 

Genbank Protein ID

 AC016727 

Genbank Nucleotide ID

  

Protein Name

 Exportin-1 

Protein Synonyms/Alias

  

Gene Name

 XPO1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
144	ILKQEWPKHWPTFIS	ubiquitination	[1]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Nucleus; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 179 AA 

Protein Sequence

Gene Ontology

 GO:0005643; C:nuclear pore; IEA:InterPro.
 GO:0008565; F:protein transporter activity; IEA:Compara.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0006611; P:protein export from nucleus; IEA:Compara.
 GO:0034504; P:protein localization to nucleus; IEA:Compara.
 GO:0010824; P:regulation of centrosome duplication; IEA:Compara.
 GO:0042176; P:regulation of protein catabolic process; IEA:Compara.
 GO:0046825; P:regulation of protein export from nucleus; IEA:Compara.
 GO:0042493; P:response to drug; IEA:Compara. 

Interpro

 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR013598; Exportin-1/Importin-b-like.
 IPR001494; Importin-beta_N. 

Pfam

 PF03810; IBN_N
 PF08389; Xpo1 

SMART

 SM00913; IBN_N 

PROSITE

 PS50166; IMPORTIN_B_NT 

PRINTS