UniProt Accession

 B4E2K3_HUMAN; B4E2K3 

Genbank Protein ID

 AC023508; AC109992; AK304312 

Genbank Nucleotide ID

 BAG65165.1 

Protein Name

 5'-3' exoribonuclease 1 

Protein Synonyms/Alias

 cDNA FLJ61552, highly similar to 5'-3' exoribonuclease 1 (EC 3.1.11.-) 

Gene Name

 XRN1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
128	LNLPRFEKYLVKLSD	ubiquitination	[1]
154	DLKWFESKVGNKYLN	ubiquitination	[1]
158	FESKVGNKYLNEAAG	ubiquitination	[1, 2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 249 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR027073; 5_3_exoribonuclease. 

Pfam

  

SMART

  

PROSITE

  

PRINTS