CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030311
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Serine/threonine kinase receptor associated protein 
Protein Synonyms/Alias
  
Gene Name
 Strap 
Gene Synonyms/Alias
 mCG_115573 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
73TLNKDATKAATAAADubiquitination[1]
122LLTGGQDKLLRIYDLubiquitination[1]
131LRIYDLNKPEAEPKEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Kinase; Receptor; Repeat; Transferase; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 350 AA 
Protein Sequence
MAMRQTPLTC SGHTRPVVDL AFSGITPYGY FLISACKDGK PMLRQGDTGD WIGTFLGHKG 60
AVWGATLNKD ATKAATAAAD FTAKVWDAVS GDELMTLAHK HIVKTVDFTQ DSNYLLTGGQ 120
DKLLRIYDLN KPEAEPKEIS GHTSGIKKAL WCSDDKQILS ADDKTVRLWD HATMTEVKSL 180
NFNMSVSSME YIPEGEILVI TYGRSIAFHS AVSLEPIKSF EAPATINSAS LHPEKEFLVA 240
GGEDFKLYKY DYNSGEELES YKGHFGPIHC VRFSPDGELY ASGSEDGTLR LWQTVVGKTY 300
GLWKCVLPEE DSGELAKPKI GFPETAEEEL EEIASENSDS IYSSTPEVKA 350 
Gene Ontology
 GO:0030054; C:cell junction; IEA:Compara.
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
 GO:0005102; F:receptor binding; IDA:MGI.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
 GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:MGI. 
Interpro
 IPR020472; G-protein_beta_WD-40_rep.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS
 PR00320; GPROTEINBRPT.