CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-039710
UniProt Accession
F5GZ78_HUMAN
;
F5GZ78
Genbank Protein ID
AC004263
Genbank Nucleotide ID
Protein Name
Paxillin
Protein Synonyms/Alias
Gene Name
PXN
Gene Synonyms/Alias
Created Date
July 27, 2013
Organism
Homo sapiens (Human)
NCBI Taxa ID
9606
Lysine Modification
Position
Peptide
Type
References
275
MASLSDF
K
IQGLEQR
ubiquitination
[1]
Reference
[1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
Mol Cell. 2011 Oct 21;44(2):325-40. [
PMID: 21906983
]
Functional Description
Sequence Annotation
Keyword
Complete proteome; LIM domain; Metal-binding; Reference proteome; Zinc.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
589 AA
Protein Sequence
MADALLADLE STTSHISKRP VFLSEETPYS YPTGNHTYQE IAVPPPVPPP PSSEALNGTI 60
LDPLDQWQPS SSRFIHQQPQ SSSPVYGSSA KTSSVSNPQD SVGSPCSRVG EEEHVYSFPN 120
KQKSAEPSPT VMSTSLGSNL SELDRLLLEL NAVQHNPPGF PADEANSSPP LPGALSPLYG 180
VPETNSPLGG KAGPLTKEKP KRNGGRGLED VRPSVESLLD ELESSVPSPV PAITVNQGEM 240
SSPQRVTSTQ QQTRISASSA TRELDELMAS LSDFKIQGLE QRADGERCWA AGWPRDGGRS 300
SPGGQDEGGF MAQGKTGSSS PPGGPPKPGS QLDSMLGSLQ SDLNKLGVAT VAKGVCGACK 360
KPIAGQVVTA MGKTWHPEHF VCTHCQEEIG SRNFFERDGQ PYCEKDYHNL FSPRCYYCNG 420
PILDKVVTAL DRTWHPEHFF CAQCGAFFGP EGFHEKDGKA YCRKDYFDMF APKCGGCARA 480
ILENYISALN TLWHPECFVC RECFTPFVNG SFFEHDGQPY CEVHYHERRG SLCSGCQKPI 540
TGRCITAMAK KFHPEHFVCA FCLKQLNKGT FKEQNDKPYC QNCFLKLFC 589
Gene Ontology
GO:0005856
; C:cytoskeleton; IEA:InterPro.
GO:0008270
; F:zinc ion binding; IEA:InterPro.
GO:0007160
; P:cell-matrix adhesion; IEA:InterPro.
Interpro
IPR001904
; Paxillin.
IPR001781
; Znf_LIM.
Pfam
PF00412
; LIM
SMART
SM00132
; LIM
PROSITE
PS00478
; LIM_DOMAIN_1
PS50023
; LIM_DOMAIN_2
PRINTS
PR00832
; PAXILLIN.